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爱普利特治疗前列腺增生患者的疗效观察

Effect of epristeride for the treatment of benign prostatic hyperplasia
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摘要 目的:观察爱普利特治疗前列腺增生(BPH)患者的疗效;方法:对32例确诊BPH的门诊患者给予爱普利特治疗。结果:服药4个月后显效18例(56.3%),有效12例(37.5%),总有效率30例(93.8%)。结论:爱普利特是一种安全、有效的治疗BPH的药物,值得临床推广使用。 OBJECTIVE To observe the effect of epristeride for the treatment of benign prostatic hyperplasia (BPH) METHODS Epristeride was given to 32 patients with the diagnosis of BPH in the clinic. RESULTS Epristeride was very ef fective in 18 cases (56. 3%) and effective in 12 cases (37.5%) with the total effective rate of 93.8%. CONCLUSION Epris teride is effective and safe for the treatment of BPH and worth for clinical use.
出处 《中国医院药学杂志》 CAS CSCD 北大核心 2009年第8期664-665,共2页 Chinese Journal of Hospital Pharmacy
关键词 爱普利特 前列腺增生 epristeride benign prostatic hyperplasia (BPH)
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参考文献3

  • 1Bartsch G, Rittmastar R S, Klocker H.Dihydrotestosterone and theconcept of 5 aipha-reductase inhibition in human benign prostatic hyperplasia[J]. Eur Urol, 2000,37 ( 4 ) : 367-380.
  • 2Sun Z Y, WU H Y, Wang M Y, etal. The mechanism of epristeride against benign pristatic hyperplasia [J]. Eur J Pharmacol, 1997,32(S1 ): S22-S27.
  • 3薛兆英,韩文科,金杰,张元芳,丁强,王晓雄,曹立军.爱普列特治疗良性前列腺增生Ⅱ期临床研究[J].中国临床药理学杂志,2000,16(6):432-435. 被引量:25

二级参考文献3

  • 1Audet P Nurcombe H,Lamb Y,Jorkasky D,et al.Effect of multipledoses of epristends, a steroid 5a-reductase inhibitor, on serumdihydrotestosterone in older male subjects[].Clinical Pharmacology and Therapeutics.1993
  • 2Johnsonbaugh RE,Cohen BR,McCormack EM,et al.Effect of fourteendays treatment with epristeride an uncompetitie 5a-reductase inhibitorOn serum and prostatic testosterone and dihydrotestosterone in men withbenign prostatic hyperpiesia[].Journal d Urologie.1993
  • 3Depre M,Meeter C,Hecken AV,et al.Pharmacodynamics and tolerability of L-654,066, a steroid 5a - reductase inhibitor, in men[].Clinical Pharmacology and Therapeutics.1992

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