摘要
通过对2019例自然流产或死胎夫妇、出生缺陷儿夫妇、不孕不育夫妇、弱智者及性器官异常者外周血淋巴细胞染色体检查结果的分析,考查了上述几类咨询人群的染色体异常频率及异常核型的分布。结果是表型异常人群染色体异常率显著高于表型正常组。弱智组主要的异常是常染色体数目改变,其次是异位。性器官发育异常组主要是性染色体数目改变;流产和出生缺陷儿夫妇组主要是结构异常、染色体易位;不孕不育组主要是性染色体数目改变。
This paper studied the Karyotypes of 2019 cases from cytogenetio clinic in our institute in 1986 -1996. According to the phenotype was normal and abnormal .the patients had divided into two group. The results proved the detection rate of abnormal karyotypes is 5. 1 per cent in normal phenotype group. 22. 17 per cent in mental retardation group. The difference is not significant (P>0.05). This study shows it is im portant to examine the chromosome in the aristogenesis working.
出处
《青岛医药卫生》
1998年第1期1-2,共2页
Qingdao Medical Journal
关键词
遗传咨询
染色体异常
Genetic counselling Chromosome abnormal karyotype
