摘要
目的研究血清γ球蛋白（γG）及胆碱酯酶与肝组织病理损害的关系．方法采用醋酸纤维薄膜法测定135例经病理证实的慢性肝炎，肝炎肝硬变及重型肝炎的血清γG；同时采用酶速率法测定他们的血清胆碱酯酶（SChE）活力结果随着肝组织纤维化程度和（或）炎症程度的加重，血清γG逐渐升高，而SChE活力则逐渐下降，差异非常显著（P＜0．01）；γG与ChE活力的相关系数为-0．612．结论血清γG的水平能准确地反映肝脏的病理损害；SChE活力能很好地反映肝脏的合成功能，肝脏的储备功能，亦能准确地反映肝脏的病理损害．
AIM To investigate the relationship between serum γglobolin and cholinesterase and the pathology of the liver.METHODS One hundred and thirty-five patients were diagnosed as chronic hepatitis, liver cirrhosis and/or severe hepatitis with needle biopsy of liver. Their serum γglobulin was determined by protein electrophoretic analysis; meanwhile their serum cholinesterase were detected by enzyme rate method.RESULTS The level of serum γ globulin increased gredully, while the level of cholinesterase decreased against the elevation of degree of fibrosis (P<0.01) and by the exacerbation of inflammatory reaction of the liver (P<0.001); The correlation coeficient between serum γglobulin and serum cholinesterase was - 0.612 (P <0.01).CONCLUSION The level of γ globulin can reflect the pathology of the liver; the level of serum cholinesterase can reflect the synthetic function and of the liver and is negatively relative with the damage of pathology of the liver.
出处
《世界华人消化杂志》
CAS
1998年第S2期212-213,共2页
World Chinese Journal of Digestology
