摘要
目的分析铜绿假单胞菌的耐药特点,指导临床用药。方法收集2005年1月至2006年12月南昌大学第一附属医院分离的189株铜绿假单胞菌,采用纸片扩散法进行药物敏感试验,数据分析采用 WHONET5.3软件。结果 189株铜绿假单胞菌分离株中,耐药率<30%的抗菌药物有哌拉西林/三唑巴坦、亚胺培南、头孢他啶、头孢吡肟和阿米卡星,其中对亚胺培南耐药率达到22.5%。结论铜绿假单胞菌耐药严重,医院应加强对铜绿假单胞菌的监测,临床要依据药敏试验结果合理用药。
Objective To investigate the antibiotic resistance of pseudomonas aeruginosa isolated from our hospital dur- ing Janury 2005 to December 2006.Methods Disc diffusion method was used to detemine the susceptibility of 189 strains of pseudomonas aeruginosa to 10 antibiotics,WHONET 5.3 was applied for analysis.Results Among 189 strains of pseudomonas aeruginosa,resistance rates to piperacillin-tazobactam,imipenem,ceftazidime,cefepime and amikacin were less than 30%.The resistance rate to imipenem reached 22.5%.Conclusion The drug resistance of PAE is seri- ous.Supervision of drug resistance of PAE should be strengthened in hospital.It's very important to select antibiotics correctly according to the results of susceptibility test in clinic.
出处
《中国实用内科杂志》
CAS
CSCD
北大核心
2007年第S1期226-227,共2页
Chinese Journal of Practical Internal Medicine
关键词
铜绿假单胞菌
抗菌药物
耐药性
Pseudomonas aeruginosa
Antibiotics
Drug resistance
