摘要
目的评价肝动脉化疗栓塞(TALE)结合骨髓间充质干细胞(MSC)输注对原发性肝癌(PHC)的疗效。方法将不能手术的晚期肝癌患者40例,随机分成治疗组(30例)及对照组(10例),均采用TALE,术后治疗组注射MSC(1.8×10~6/kg),观察两组疗效及生存率。结果两组治疗后1、2年肿瘤局部有效率分别为90%、60%。1～2年生存率分别为90%、30%,治疗组中位生存期15个月。结论TALE结合MSC输注是治疗PHC的有效微创治疗手段。
Objective To evaluate the efficiency of primary hepatic carcinoma(PHC)using tran- scatheter arterial chemoembolization(TALE)combining with MSC.Methods Treatment group(30 patients with unresectable PHC)adopt MSC after TALE,while control group(10 patients with unresectable PHC)only adopt TALE,then observing the curative effect and survival rate.Results One year after treating,the local effect was 90 %,60 %,1～2 year survival rate was 90 %,30 % respectively,median life span was 15 months. Conclusion To treat PHC with TALE combining with MSC is an effective and non-invasive method.
出处
《肿瘤研究与临床》
CAS
2007年第4期250-251,253,共3页
Cancer Research and Clinic
关键词
肝肿瘤
化学栓塞
治疗性
骨髓间质干细胞
Liver neoplasms
Chemoembohzation,therapeutic
Mesenchymal stem cell
