摘要
目的 :探讨三才封髓丹对小鼠红系细胞造血的作用机理。方法 :通过应用三才注射液对贫血及正常小鼠外周血的Hb、RBC、网织红细胞 (Ret)、红系分裂指数、骨髓有核细胞(BMC)进行测定及采用红系造血祖细胞 (burstformingunit erythroid ,BFU E ;colonyformingunit erythroid ,CFU E)的培养方法 ,观察三才封髓丹的造血作用。 结果 :三才封髓丹能促进贫血小鼠的Hb、RBC、Ret、红系分裂指数、BMC的增加 ,在脾细胞或腹腔巨噬细胞条件下 ,能促进BFU E及CFU E的增殖。结论 :三才封髓丹可能是通过激活红系造血调控因子而促进造血功能。
Objective: To study the effective mechanism of Sancai Fensui Dan in mice.Methods: Sancai injection (SCI) was given to normal or anemia mice and their hemoglobin (Hb), red blood cell (RBC), reticulocyte (Ret) of peripheral blood, mitosis index (MI) of red cells, bone marrow nucleated cell (BMC) were measured. And the cultured hemopoietic progenitor cells of burst forming unit erythroid (BFU E) and colony forming unit erythroid (CFU E) were used to observe the hemopoiesis effect of SCI. Results: SCI could promote the increase of Hb, RBC, Ret, MI and BMC in anemia mice. At the presence of spleen cells or macrophages in peritoneal cavity, it could enhance the proliferation of BFU E and CFU E.Conclusion: SCI could promote hemopoiesis by activating the hemo opsonin.
出处
《中国中西医结合杂志》
CAS
CSCD
北大核心
1998年第3期165-167,共3页
Chinese Journal of Integrated Traditional and Western Medicine
基金
黑龙江省科学技术委员会资助课题!(No.G92C2 40 80 5 0 2 )
关键词
三才封髓丹
红系造血祖细胞
脾细胞
巨噬细胞
Sancai Fengsui Dan ,hemopoietic progenitor cell of red blood cell line, spleen cell, macrophage
