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微量白蛋白尿在原发性高血压中的研究进展 被引量：16

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摘要 微量白蛋白尿（MA）是指尿中白蛋白水平超过健康人参考范围。目前研究发现，微量白蛋白尿不仅是。肾脏疾病并发症的预测指标，也是心血管疾病的独立危险因素，是高血压血管损伤的敏感指标，对于早期治疗原发病、分析病程进展、评价相关危险因素具有重要意义。故美国JNC7和2007欧洲高血压防治指南将血浆肌酐、尿白蛋白排泄率或尿白蛋白肌酐比值作为高血压患者危险分层的指标之一。
作者 王方芳 杨冬花 李昭屏
机构地区 北京大学第三医院心内科 贵阳中医学院第二附属医院心内科
出处 《中国心血管病研究》 CAS 2009年第4期305-307,共3页 Chinese Journal of Cardiovascular Research
关键词 微量白蛋白尿 原发性高血压 Microalbuminuria Essential hypertension
分类号 R544.1 [医药卫生—心血管疾病]
  • 相关文献

参考文献21

  • 1Chobanian AV,Bakris GL,Black HR,et al.The seventh report of the joint national committee on prevention,detection,evaluation,and treatment of high blood pressure:the JNC 7 report.JAMA,2003,289:2560-2572.
  • 2Mancia G,de Backer G,Dominiczak A,et al.2007 Guidelines for the Management of Arterial Hypertension:the Task Force for the Management of Arterial Hypertension of the European Society of Hypertonsion (ESH) and of the European Society of Cardiology (ESC).J Hypertens,2007,25:1105-1187.
  • 3Sierra A,Egocheaga MI,Aguilera MT.Prevalence and clinical characteristics of microalbuminuria in the Spanish hypertensive population.Med Clln (Barc),2008,130:201-205.
  • 4Pruijm MT,Madeleine G,Riesen WF,et al.Prevalence of microalbuminuria in the general population of seychelles and strong association with diabetes and hypertension independent of markers.J Hypertens,2008,26:871-877.
  • 5Cottone S,Mule G,Nardi E,et al.Microalbuminuria and early endothelial activation in essential hypertension.J Hum Hypertons,2007,21:167-172.
  • 6Rnsso LM,Comper WD,Osicka TM.Mechanism of albuminuria associated with cardiovascular disease and kidney disease.Kidney Int Suppl,2004,92:S67-68.
  • 7Basi S,Lewis JB.Microalbuminuria as a target to improve cardiovascular and renal ontcomes.Am J Kidney Dis,2006,47:927-946.
  • 8Ferroni P,Guagnano MT,Falco A,et al.Association of low-grade inflammation and platelet activation in patients with hypertension with microalbuminuria.Clin Sci (Lond),2008,114:449-455.
  • 9Pedrinelli R,Dell'Omo G,Penno G,et al.Mpha-adducin and angiotensin-converting enzyme polymorphisms in hypertension:evidence for a joint influence on albuminuria.J Hypertens,2006,24:931-937.
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二级参考文献14

  • 1王珍,邵华.高血压前期人群合并代谢综合征的聚集情况[J].温州医学院学报,2004,34(4):285-287. 被引量：7
  • 2华琦.解读《中国高血压防治指南》(2005年修订版)(一) 高血压诊疗新进展[J].中国心血管病研究,2006,4(2):85-88. 被引量：157
  • 3[1]Craig KJ,Donovan K,Munnery M,et al.Identification and management of diabetic nephropathy in the diabetes clinic.Diabetes Care,2003,26:1806-1811.
  • 4[2]Paltini P,Mormino P,Mos L,et al.Microalbuminuria,renal function and development of sustained hypertension:a longitudinal study in the early stage of hypertension.J Hypertens,2005,23:175-182.
  • 5[3]Hillege HL,Fidler V,Diercks GF,et al.Urinary albumin excretion predicts cardiovascular and noncardiovascular mortality in general population.Circulation,2002,106:1777-1782.
  • 6[4]Borch-Johnsen K,Feldt-Rasmussen B,Strandgaard S,et al.Urinary albumin excretion an independent predictor of ischemic heart disease.Arterioscle Thromb Vasc Biol,1999,19:1992-1997.
  • 7[5]Sukhija R,Aronow WS,Kakar P,et al.Relation of microalbuminuria and coronary artery disease in patients with and without diabetes mellitus.Am J Cardil,2006,98:279-281.
  • 8[7]Meigs JB,Jacques PF,Selhub J,et al.Fasting plasma homocysteine levels in the insulin resistance syndrome:the Framingham offspring study.Diabetes Care,2001,24:1403-1410.
  • 9[9]Nakamura M,Onoda T,Itai K,et al.Association between serum C-reactive protein levels and microalbuminuria:a population-based cross-sectional study in northern Iwate Japan.Intern Med,2004,43:919-925.
  • 10[10]Erbagci AB,Tarakcioglu M,Coskun Y,et al.Mediators of inflammation in children with type 1 diabetes mellitus:cytokines in type 1 diabetic children.Clin Biochem,2001,34:645-650.

共引文献15

同被引文献173

引证文献16

二级引证文献77

中国心血管病研究
2009年 第4期

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