摘要
目的:评价消化道肿瘤肝转移瘤介入治疗的临床疗效及影响因素。方法:采用改良Seldinger法经股动脉插管,以灌注化疗及化疗栓塞进行治疗,化疗药物依病理分型而定,栓塞剂采用超液化碘油混以一种化疗药物制成。适当应用超微导管技术。结果:全组102例共行次438介入治疗,其中单纯灌注化疗137次,加碘油栓塞301次,使用微导管108例次。总有效率达57.3%,(0.5,1,2,3,5)年生存率分别为84.9% ,71.7% ,32.9% ,7. 1%,1.4%。结论:肝动脉介入治疗消化道肿瘤肝转移瘤仍是目前首选的治疗方法。依病理分型选择化疗药物,碘油均匀沉积,富血供和超选择微导管技术对治疗效果有重要影响。
Objective： to evaluate the clinical effect and influencing factor of interventional therapy in the treatment of liver metastases from alimentary tract cancer.Methods： With the means of improvement Seldinger femoral artery cannula,it was performed with infusion chemotherapy,chemoembolization and the of technology ultraselection microtubule.The choice of chemotherapeutics was depend on the type of pathology.Results：A total of 102 patients with unresectable liver metastases from alimentary tract cancer was treated 438 times by interventional therapy.Of the 438 times,only infusion chemotherapy was performed at 137 times,and infusion chemotherapy and lipiodol embolization at 301 times.Ultraselection microtubule was carried out at 108 times.The 0.5,1,2,3 and 5 year survival rate of standard group was 84.9%,71.7%,32.9%,7.1%and 2.4%.Conclusion：Treatment by hepatic artery interventional therapy is the first method to patients with liver metastases from alimentarytractcancer.Pathological typing,lipiodol embolization,vascular abundant and the technology of ultraselection microtubule have important influence on therapeutic efficacy.
出处
《中国医药导刊》
2009年第1期22-23,共2页
Chinese Journal of Medicinal Guide
关键词
消化道肿瘤
肝转移瘤
介入治疗
Digestive system neoplasm
Liver neoplasms
Interventional therapy
