摘要
人类疱疹病毒8型广泛存在于各种临床表型的Kaposi肉瘤中，其基因型分布呈现种族与地域特异性。了解Kaposi肉瘤患者中HHV-8基因型特征及分布情况，探讨其与Kaposi肉瘤临床可能的相关性和演变及传播等具有重要意义。并对HHV-8病毒体及其基因组特征，K1和K15基因位点的生物学功能，HHV-8基因型演变呈现地域与种族特异性进行概述。
Human herpesvirus 8 （HHV-8） exists widely in the tissue of various clinical phenotypes of Kaposi＇s sarcoma （KS）. The distribution of HHV-8 genotype shows a race and geographical specificity. So, it is important to understand the characteristic and distribution of HHV-8 genotype, and to explore the possible relationship of HHV-8 genotype to clinical phenotypes of KS as well as the transmission and evolution of HHV-8. This article gives a review on the race and geographical specificity of evoluation of HHV-8 genotype.
出处
《国际皮肤性病学杂志》
2009年第2期127-129,共3页
International Journal of Dermatology and Venereology
