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拉米夫定治疗活动性肝炎肝硬化疗效观察

The curative observation of Lamivudine in treatment of the active hepatitis and hepatocirrhosis
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摘要 目的:观察拉米夫定治疗活动性肝炎肝硬化的近期疗效。方法:观察组在基础护肝下加用拉米夫定(100mg/d)治疗。对照组仅基础护肝、对症,均治疗1年,观察治疗前后患者症状、体征、肝功能和乙肝病毒复制指标。结果:观察组症状、体征、肝功能显著改善,HBeAg、HBVDNA阴转率显著高于对照组。结论:拉米夫定治疗活动性肝炎肝硬化的近期疗效明显、安全,未见明显不良反应。 Objective: To observe Lamivudine' s recent healing effect of curing the active hepatitis and hepatocirrhosis. Methods : To observe the treatment of 48 patients by using more Lamivudine (100mg/d) under the basic liver protection. All of the matched groups are only based on basic liver protection and all are cured for a year, then observe the patients' symptom, physical sign, liver function and virus duplicate index of hepatitis B before and after the treatment. Results: Observation groups' symptom, physical sign and liver functioo improved greatly. The negative conversion rates of HBeAg and HBVDNA are higher than matched groups. Conclusion: Lamivudine' s treatment of active hepatitis and hepatocirrhosis is very good, safe and no adverse reaction.
出处 《赣南医学院学报》 2009年第1期46-47,共2页 JOURNAL OF GANNAN MEDICAL UNIVERSITY
关键词 活动性肝炎 肝硬化 拉米夫定 the active hepatitis hepatocirrhosis Lamivudine
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