摘要
着色芽生菌病是由一组暗色真菌引起的皮肤和皮下组织感染性的慢性真菌病，呈全球性分布。组织病理改变主要表现为3个方面：表皮假上皮瘤样增生、化脓性肉芽肿性炎、纤维增生机化。确诊依靠真菌培养及组织病理学找到棕色厚壁孢子，分子生物学技术（DNA技术）为该病的研究提供了新的手段。本文对其流行病学、微生物学、临床病理表现、实验室诊断和鉴别诊治等方面的研究现状进行综述，提高对该病的认识。
Chromoblastomycosis is a chronic fungus disease on skin or subcutaneous tissue caused by a group of dematiaceous fungi with global distribution. Pseudoepitheliomatous hyperplasia, suppurative granuloma inflammation and fibroplasia organization were regarded to the three main histopathological changes associated with these diseases. The final diagnosis of this disease depends on fungus culture and histopathological observation on the brown thick wall spore, and molecular biology technology （the DNA technology） provide some new methods for research on this disease. This article reviewed the present situations of chromoblasto- mycosis in epidemiology, microbiology, clinical pathology performance, laboratory diagnosis and distinction diagnosis in order to enhance our understanding.
出处
《医学综述》
2009年第6期851-853,共3页
Medical Recapitulate
关键词
着色芽生菌
诊断
进展
Chromoblastomycosis
Diagnosis
Progress
