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他汀类药物降脂治疗2008:新的证据与挑战 被引量:3

Statins therapy in 2008: new evidences and new challenge
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摘要 血清低密度脂蛋白-胆固醇(LDL-C)升高是心血管疾病的一个重要危险因素。低水平LDL-C维持时间越长,心血管危险降低越显著;LDL-C水平降低越多,心血管危险降低越多,尤其是对已经存在明显动脉粥样硬化疾病的患者。对临床医师来说,如何更好地降低人群LDL-C水平是项艰巨的挑战,要完成这样的使命,可能需要我们对心血管防治体系进行反思。 Elevated serum low-density lipoprotein-cholesterol(LDL-C)is a major risk factor for cardiovascular diseseses. The longer the low LDL-C level is kept, the better for risk reduction. The lower the LDL-C level that is achieved, the greater the risk reduction will be, particularly in patients with advanced atherosclerotic disease. The major challenge for the physicians is how best to achieve LDL-C lowering in general population. This likely will require a rethinking of the medical and public health models of prevention.
作者 李勇
出处 《世界临床药物》 CAS 2009年第3期129-136,共8页 World Clinical Drug
关键词 他汀类药物 一级预防 二级预防 安全性 statins primary prevention secondary prevention safety
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