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一些含噻唑杂环的萘酰亚胺衍生物的合成

Synthesis and characterization of some derivatives of 1,8-naphthalimides containing thiazole heterocyclics
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摘要 以6-溴-1H,3H-苯并[de]吡喃-1,3-二酮为起始原料,通过硝化、氢化还原、关环和亚酰化反应,合成了3个含噻唑杂环的萘酰亚胺衍生物:N-丙基-9-苯基-苯并[de]噻唑[4,5-g]异喹啉-4,6-二酮、N-丁基-9-苯基-苯并[de]噻唑[4,5-g]异喹啉-4,6-二酮和N-羟乙基-9-苯基-苯并[de]噻唑[4,5-g]异喹啉-4,6-二酮。产物经过IR1、HNMR和元素分析进行了表征。 Starting from 6-bromo-1H,3H-benzoisochromene-1,3-dione,three new compounds——N-propyl-9-phenyl-benzo-[de]-thiazole-[4,5-g]-isoquinoline-4,6-dione,N-butyl-9-phenyl-benzothiazole-[4,5-g]-isoquinoline-4,6-dione and N-hydroxyethyl-9-phenyl-benzothiazole-[4,5-g]-isoquinoline-4,6-dione were synthesized through the reactions of nitration,hydrogenation,cyclization and imidation.The compounds were characterized by IR,1HNMR and elemental analyses.
作者 覃雯 徐健飞 刘茜 张业
机构地区 桂林师范高等专科学校化学与工程技术系 广西师范大学化学化工学院 梧州学院教师教育系
出处 《化学试剂》 CAS CSCD 北大核心 2009年第3期200-202,共3页 Chemical Reagents
基金 国家自然科学基金资助项目(20362002,2076-2001)
关键词 合成 萘酰亚胺 噻唑 杂环 表征 synthesis naphthalimides thiazole heterocyclics characterization
分类号 O626 [理学—有机化学]
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参考文献12

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二级参考文献8

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化学试剂
2009年 第3期

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