摘要
目的分析胰腺神经内分泌肿瘤的外科治疗策略及影响预后的因素。方法回顾性分析1999年4月至2007年5月之间经手术治疗且病理证实的30例胰腺神经内分泌肿瘤患者的临床资料。根据WHO新的分级标准，对肿瘤大小、手术方式、病理类型与远期生存之间的关系进行分析。结果30例患者中男性18例，女性12例；平均年龄54岁（28～78岁）；5例失访，获得随访的25例患者中，良性20例、恶性5例；良、恶性组中位生存时间分别为74．8和33．8个月（x^2=8．90，P=0．003）。全组1、2、3、4、5年生存率分别为100％、100％、82．0％、82．0％、65．6％。结论胰腺内分泌肿瘤是一类比较少见的胰腺肿瘤。手术切除可获得良好的长期生存。新的WHO分型方法可以比较有效地预测肿瘤的预后。
Objective To analyze the surgical treatment strategy anti prognostic factors of panereatic neuroendocrine tumor. Methods The clinical data of 30 patients who underwent pancreatic surgery in our department from April, 1999 to May, 2007 were retrospectively reviewed. According to the new WHO classification system, factors possibly influence the long term survival, such as tumor size, operation types, pathological types, were analyzed. Results There were 18 males and 12 females, with a mean age of 54 years old （28 - 78 years old）. Five patients were lost in follow up. Among 25 patients who were completely followed, 20 cases were benign and other 5 were malignant, the median survival time of benign and malignant group was 74.8 months and 33.8 months, respectively （ X2 = 8.90, P = 0. 003 ）. Overall 1 , 2, 3, 4, 5-year survival rates were 100% , 100% , 82. 0% , 82. 0% , 65. 6% , respectively. Conclusions Pancreatic neuroendoerine tumor was a rare type of tumor of the pancreas with a good prognosis if surgically resected. The new classification method was effective in predicting the prognosis.
出处
《中华胰腺病杂志》
CAS
2009年第1期18-20,共3页
Chinese Journal of Pancreatology
关键词
胰腺
神经内分泌瘤
外科手术
生存
Pancreas
Neuroendocrine tumors
Surgical procedures, operative
Survival
