摘要
目的:比较静脉与硬膜外病人自控镇痛(PCIA、PCEA)在术后镇痛中的临床效果。方法:选术后病人180例,随机分成PCIA组、PCEA组和对照组。结果:前两组病人术后镇痛效果均无显著差异;PCIA组尿潴留的发生率明显低于PCEA组(P<0.05);PCEA组的肠蠕动恢复明显快于PCIA组(P<0.01);两组病人恶心呕吐、皮肤瘙痒、呼吸抑制发生率无显著差异;PCIA组病人中有10%镇静达中度,而PCEA组无1例发生明显镇静现象;未行镇痛组术后6h血清皮质醇明显高于行PCA镇痛者(P<0.01)。结论:PCIA,PCEA均达到较好的镇痛效果,减轻术后应激反应。PCIA尿潴留发生率低,但易发生明显镇静,且肠蠕动抑制较PCEA明显。
To compare the clinical effect and side-effect of intravenous PCA(PCIA) with epidural PCA (PCEA). Method: One hundred and eighty postoperative patients, who were randomly divided into three groups: group PCIA, group PCEA and control, were observed for 3 days after operation. Result: Overall patients in two PCA groups were satisfied with the postoperative analgesia. The incidence of urinary retention in group PCIA were significantly lower than that in group PCEA (P<0.05). The recovery of bowel movement in group PCEA were much more rapidly than that in group PCIA (P<0.05). There were no remarkable differences between two PCA groups in nausea, vomiting, respiratory depression and pruritis(P>0.05). 10% in group PCIA were in medium sedation whereas no eases in group PCEA were in sedation. At 6th hour after operation,serum cortisol level of control patients was much higher than that of PCA patients. Conclusion=Both PCIA and PCEA have excellent analgesia and reduce stress response after operation. PClA has lower incidence of urinary retention and is performed easily,but inhibits gastrointestinal motility much more and has higher sedative incidence compared with PCEA.
出处
《中华麻醉学杂志》
CAS
CSCD
北大核心
1998年第4期251-253,共3页
Chinese Journal of Anesthesiology
关键词
疼痛
术后
镇痛
吗啡
静脉
注射
硬膜外腔
Pain, postoperative Analgesia, patient controlled Morphine Infusions, intravenous Injections, epidural
