摘要
目前已从不同物种、不同种类细胞中筛选到很多关卡基因和蛋白质，如ＡＴＭ、ＲＡＤ５３、ＣＨＫ１等．有关它们在具体关卡调控途径中的作用，以及和癌变发生的关系已有许多报道．
Many checkpoint genes and proteins have been screened from different species and cells until now, such as ATM, RAD53, CHK1 etc. There are a lot of reports about their function in checkpoint control pathways as well as the correspondances with cancers.
出处
《生物化学与生物物理进展》
SCIE
CAS
CSCD
北大核心
1998年第2期110-114,共5页
Progress In Biochemistry and Biophysics
关键词
细胞周期
关卡调控途径
细胞癌变
cell cycle, checkpoin control pathway, cell carcinogenesis
