摘要
目的以^(18)F-FDG PET心肌代谢显像为标准,评价64层螺旋CT心脏延迟增强扫描对心肌存活性的诊断价值。方法20例急性心肌梗死患者,初次心肌梗死发作2周内接受64层螺旋CT及PET检查。按照美国心脏学会推荐的方法将左心室心肌分为17节段。逐个节段进行对比并用配对McNemar检验及诊断试验一致性检验进行统计分析,了解两种方法的一致性。结果左心室心肌的17个节段中,5段心肌两种方法检测结果完全一致。10段心肌一致性好(Kappa值>0.75),2段检测结果显示两种方法一致性较好(0.40≤Kappa值≤0.75)。结论64层螺旋CT心脏延迟增强扫描与PET评估心肌存活性具有很好的一致性,是一种有临床应用前景的评估存活心肌的新方法。
Objective To assess the diagnostic value of myocardial viability by delayed-enhancement 64-slice CT compared with ^（18）F-FDG PET imaging in patients with acute myocardial infarction.Methods Twenty patients with first acute myocardial infarction outbreak underwent delayed enhancement multi-slice computed tomography（DE-MSCT）and ^（18）F-FDG PET image within two weeks.The 17 segments of the left ventricle depicted by the American Heart Association were graded：no, subendocardial,or transmural hyperenhancement on DE-MSCT.No or subendocardial hyperenhancement were expected to reflect viability.In order to determine the agreement of two methods,data of 17 myocardial segments were analyzed respectively by McNemar test and Kappa test.Results All patients were in sinus rhythm.Myocardial infarction was anterior（n= 8）,anteroseptal（n=3）,inferior（n=9）.Analysis of assessment of myocardial viability revealed best agreement among 5 myocardial segments（Kappa=1）,better agreement among 10 myocardial segments（Kappa〉75）and good agreement between 2 myocardial segments（0.40≤Kappa≤0.75）.Conclusion There is high agreement between DE-MSCT and ^（18）F-FDG PET imaging in the diagnosis of acute myocardial infarction.DE-MSCT is a promising method for assessment of myocardial viability.
出处
《中国医学影像技术》
CSCD
北大核心
2009年第2期301-304,共4页
Chinese Journal of Medical Imaging Technology
基金
上海市领军人才培养基金(LJ06006)。
关键词
心肌活力
体层摄影术
发射型计算机
X线计算机
Myocardial viability
Tomography,emission computed
Tomography,X-ray computed
