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槲芪散联合经动脉化疗栓塞术治疗原发性肝癌65例临床观察 被引量:18

Clinical Observation of 65 Cases with Hepatocellular Carcinoma Treated by Huqisan and Transeatheter Arterial Chemoembolization
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摘要 目的观察中药复方槲芪散联合经动脉化疗栓塞术治疗原发性肝癌对患者生存时间、生活质量及免疫功能的影响。方法65例原发性肝癌患者用数字表法随机分为槲芪散治疗组和对照组,对照组给予槐耳颗粒,均治疗24周。比较2组患者外周血T淋巴细胞亚群和生活质量(KPS评分)变化、生存时间及临床总证候疗效。结果槲芪散治疗组在外周血T淋巴细胞亚群和生活质量(KPS评分)变化、生存时间及临床总证候疗效方面均优于对照组。结论槲芪散联合动脉化疗栓塞治疗原发性肝癌可明显提高总有效率,改善患者生活质量,延长生存期,提高患者细胞免疫功能,对肝癌的介入治疗可发挥增效减毒的作用。 Objective To observe the joint effects of Chinese medicine Huqisan (HQS) and transcatheter arterial chemoembolizatiou(TACE) in patients with hepatocellular carcinoma (HCC) on survival time, quality of life and immune function. Methods Sixty-five patients with HCC were randomly divided into two groups: the treatment group with HQS and TACE, and the control group with Huaier Keli. After the treatment for 24 weeks, the differences in peripheral T-lymphocyte subsets, quality of life ( KPS ) , survival time and clinical efficacy of the overall syndrome were analyzed. Results The treatment group was better than the control group in terms of peripheral blood T-lymphocyte subsets, the quality of life(KPS) , survival time and clinical efficacy of the overall syndrome. Conclusion The treatment of HQS and TACE for HCC may improve the overall efficacy and the quality of life, survival time and cell immune function of patients.
出处 《首都医科大学学报》 CAS 北大核心 2009年第1期37-40,共4页 Journal of Capital Medical University
基金 首都医学发展基金(2005-FSF-Ⅲ-105)资助项目~~
关键词 原发性肝癌 槲芪散 经动脉化疗栓塞 免疫功能 槐耳颗粒 hepatocellular carcinoma Huqisan transeatheter arterial chemoembolization immune function Huaierkeli
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参考文献3

  • 1叶任高,陆再英.内科学[M].6版.北京:人民卫生出版社,2005:64.
  • 2Liapi E, Georgiades C C, Hong K, et al. Transcatheter arterial chemoembolization: current technique and future promise[J]. Tech Vasc Interv Radiol, 2007,10:2 11.
  • 3Camma C, Schepis F, Orlando A, et al. Transarterial chemoembolization for unresectable hepatocellular carcinoma: metaanalysis of randomized controlled trials[ J]. Radiology, 2002,224:47-54.

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