摘要
目的探讨肛管恶性黑色素瘤的临床病理特点,提高诊断水平。方法对1例肛管恶性黑色素瘤临床病理资料进行分析,并行组织病理学(HE)和免疫组化(SP法)观察。结果该肿瘤临床表现多为肛门脱出肿物,镜下呈浸润性生长,瘤细胞呈上皮样,部分含有色素,呈巢状,梁索状排列。免疫表型表达S-100和HMB-45。结论肛管恶性黑色素瘤罕见,临床表现复杂。镜下肿瘤具有特征性的组织学和免疫组化表现。预后大多较差。
Purpose To investigate characteristics of anal malignant melanoma for observation.Prognosis is poor in most case. improvement of its diagnosis. Methods one case of anal malignant melanoma was studied using routine histopathology（HE staining） and immunohistochemistry（SP）.Clinicopathologyical characteristics were then described. Results The main clinic symptom was visible or palpable mass in the anus.Under microscope,the tumor cell was showing invasive growth like ethelioid type,some of tumor cell have melanin granules.its arrangement was like nest or cords.Immunohistochemically, the tumor was positive for S-100 and HMB-45 markers. Conclusion Anal malignant melanoma is rare. Its clinic symptom is complicated.This tumor has a characteristic appearance by microscopy and immunohistochemical
出处
《当代医学》
2009年第4期92-93,共2页
Contemporary Medicine
关键词
肛管
恶性黑色素瘤
病理学
临床
免疫组化
anal
malignant melanoma
misdiagnosis
clinicopathology
immunohisto-chemistry
