摘要
目的:提高对肺曲霉菌病的认识,制定合理治疗方案。方法:对我院21例诊断肺曲霉菌病患者的临床资料进行回顾分析。结果:所有患者均有基础疾病,长期应用糖皮质激素9例(42.9%),使用多种抗生素超过3周18例(85.7%),机械通气9例(42.9%),深静脉置管8例(38%),白细胞减少6例(28.6%)。其中,过敏型肺曲霉菌病3例(14.3%);寄生型肺曲霉菌病5例(23.8%);侵袭型肺曲霉菌病13例(61.9%)。死亡5例(23.8%),治愈或好转16例(76.2%)。结论:肺曲霉菌病患者多患有基础疾病,并存在多种危险因素。诊断主要根据病史、影像学表现和痰培养结果,确诊依赖于肺组织内发现曲霉菌丝。应根据肺曲霉菌病诊断分型的不同,分别选择激素、手术、药物等不同的治疗方法。
Objective： To promote recognition of pulmonary aspergillosis and develop appropriate clinical treatment for the disease. Methods： The clinical features of 21 cases of pulmonary aspergillosis were analyzed in our hospital. Results： All 2l patients had primary diseases. 9 patients were administered glucocorticoids chronically （42.9%） ; 18 were administered antibiotics for more than 3 weeks （85.7%）; 9 were treated with mechanical ventilation （42.9%）; 8 were treated with deep venous catheter （ 38% ） ; and 6 had leucopenia （28.6%）. Among the 21 cases, 3 patients had allergic pulmonary aspergillosis （14.3%）, 5 had parasitic pulmonary aspergillosis （23.8%）, and 13 had invasive pulmonary aspergillosis （61.9%）. 5 patients died （23.8%）. 16 were cured or improved （76.2%）. Conclusion： Most patients with pulmonary aspergillosis have pri- mary diseases accompanied with risk factors. Diagnoses are made based on past medical history, chest radiography and sputum culture, and confirmed according to aspergillus found in pulmonary tissue. Different treatments such as glucocorticoids, surgery or medication should be used according to different types of pulmonary aspergillosis.
出处
《军医进修学院学报》
CAS
2009年第1期62-64,共3页
Academic Journal of Pla Postgraduate Medical School
关键词
曲霉菌病
变应性支气管肺
基础疾病
危险因素
诊断
治疗
aspergillosis, allergic bronchopulmonary
primary diseases
risk factors
diagnosis
therapy
