摘要
结直肠癌是最常见的恶性肿瘤之一,有近一半会进展为肝转移,外科治疗是惟一可以获得长期生存并具有潜在治愈性可能的方法,20%～30%的结直肠癌肝转移患者能够从手术中获益,5年生存率为37%～58%。为了使更多的患者可以接受手术治疗,新技术不断发展,如新辅助化疗、门静脉栓塞术、肝动脉介入治疗以及射频消融联合手术。目前如何拓展手术适应证成为研究的热点。
Colorectal cancer is one of the commonest cancers world wide. Roughly one half of patients with colorectal cancer develop liver metastases during their disease course. Hepatic resection for colorectal live metastases has become the standard of care and currently remains the only potentially curative therapy. Hepatectomy offers the best chance of cure in 20 - 30% of patients with potentially reseetia- ble metastases, with varied 5-year survival rates ranging 37 -58%. Many efforts have been made to in- crease the number of patients who could benefit from hepatic resection, including neoadjuvant systemic and regional chemotherapy, pre-operation portal vein embolization for hypertrophy of future liver remnant, and radio frequency ablation combined with resection for addressing multiple bilobar metastases. This review briefly covers the standard techniques currently employed and the recent innovation that has been a- dopted to extend the frontiers of surgical therapy for eolorectal hepatic metastases.
出处
《癌症进展》
2009年第1期34-38,共5页
Oncology Progress
关键词
结直肠癌
肝转移
外科学
colorectal cancer liver metastasis surgery
