摘要
目的观察肌内注射胎盘组织液辅助食管扩张治疗食管胃吻合口狭窄的疗效。方法食管胃吻合口狭窄（除外癌复发）患者127例分为2组。A组：88例。吻合口直径0.5～0.8 cm,其中采用单纯肌内注射胎盘组织液40例,采用扩张治疗48例。B组：39例。吻合口直径〈0.5 cm,其中采用肌内注射胎盘组织液联合扩张法18例,采用单纯扩张治疗21例。结果A组：单纯肌内注射胎盘组织液与扩张法在有效率、并发症发生率、复发率上差异无统计学意义（P〉0.05）,扩张次数明显低于后者（P〈0.01）;B组：扩张组和联合治疗组在有效率、并发症发生率、复发率上差异无统计学意义,在扩张次数上B扩张组明显多于联合组（t=2.047,P=0.0478）。结论肌内注射胎盘组织液可以有效减少食管胃吻合口狭窄扩张治疗次数。
Objective To observe the therapeutic effect of dilation combined with intramuscular injection with human placenta tissue hydrolysate （HPTH） on anastomotic stenosis after esophagogastrostomy. Methods 127 patients with esophagogastronic anastomotic stenosis into two groups： 88 patients in group A （diameter of anastomoses 0. 5 - 0. 8 cm）, in whom 40 patients were treated with HPTH, the other 4,8 patients were treated with dilation; 39 patients in group B（ diameter of the anastomoses 〈0.5 cm）, 18 patients were treated with HPTH and dilation, the other 21 patients were treated with dilation only. Results In group A, there were no significant differences in efficacy, complication incidence, recurrent rate between two methods, but there are great differents on dilation time （ P 〈0.01）. In group B, there were no significant differences in efficacy, complication incidence, recurrent rate between two methods, but the dilation times in simple dilation group were significantly more than those of HPTH and dilation group （ t = 2. 047, P = 0. 0478）. Conclusion Intramuscular injection with HPTH can reduce the dilation times in the treatment of anastomotic stenosis after esophagogastrostomy.
出处
《河北医药》
CAS
2009年第1期37-38,共2页
Hebei Medical Journal
关键词
食管癌
贲门癌
吻合口狭窄
扩张术
胎盘组织液
esophagus carcinoma
gastric cardiac carcinoma
anastomotic stenosis
dilation
human placenta tissue hydrolysate
