摘要
目的:观察弥可保联合西沙必利治疗糖尿病胃轻瘫的疗效.方法:72例糖尿病胃轻瘫随机分为治疗组38例和对照组34例:在常规治疗糖尿病的同时,治疗组应用西沙必利10mg每日3次,加用弥可保500μg肌注,每日1次,连用4wk;对照组只服用西沙必利,其剂量、用法和疗程与治疗组相同.比较两组治疗前后的临床症状及停药1mo后的复发率.结果:治疗4wk后,与对照组比较,治疗组有效率有显著差异(94.7%vs76.5%,P<0.01),且停药后1mo内对照组复发率97.1%,而治疗组为39.5%(P<0.0l).结论:弥可保联合西沙必利对糖尿病胃轻瘫有良好的治疗作用.
AIM： To evaluate the effects of methycobal and Cisapride in treatment for patients with diabetic gastropathy （DG）. METHODS： Seventy two DG patients were randomly divided into treatment group （n = 38） and control group （n = 34）. The treatment group received Cisapride （10 mg, three times a day） and intramuscular administration of methycobal for 4 weeks. The control group received routine treatment with the equivalent dosage as the treatment group. Clinical symptoms before and after treatment and relapse rate 1 month after withdrawal of drugs were observed and compared between the treatment group and control group. RESULTS： After 4 weeks＇ treatment, the effective rate in treatment group was significantly different from the control group （94.7% vs 76.5%, P 〈 0.01）. And after Ⅰ month, the recurrence rate of the control group was 97.1%, while it was 39.5% in the treatment group （P 〈 0.01） CONCLUSION： Treatment of methycobal in combination with cisapride shows nice therapeutic effect for diabetic gastroparesis.
出处
《世界华人消化杂志》
CAS
北大核心
2009年第2期202-204,共3页
World Chinese Journal of Digestology
