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生大黄粉防治重型颅脑损伤后上消化道出血疗效观察 被引量:2

Effect of Rhubarb on 89 Patients with Upper Digestive Tract Bleeding after Severe Cerebral Injury
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摘要 目的:观察生大黄粉在颅脑损伤后上消化道出血防治中的效果。方法:将167例颅脑损伤患者随机分为两组,实验组89例,应用生大黄粉和泮托拉唑。对照组78例,应用泮托拉唑。观察两组临床疗效,依胃液隐血试验结果判定。结果:两组中开始无消化道出血者,治疗组出现5例上消化道出血,对照组7例(P<0.05)。28例上消化道出血患者中,实验组上消化道出血治愈率显著高于对照组(P<0.05);实验组上消化道出血治愈平均时间显著短于对照组(P<0.05)。结论:重型颅脑损伤后早期鼻饲生大黄粉可显著降低上消化道出血发病率,提高上消化道出血治愈率,缩短出血治愈疗程。 Objective :To observe the effect of rhubarb on 89 patients with upper digestive tract bleeding after severe cerebral injury. Methods :167 patients after cerebral injury were randomly divided into two groups ,89 patients in trial group were prescribed with rhubarb and pantoprazole sodium, while 78 patients in control group were used only pantoprazole sodium. Results : There are 5 patients who were judged upper digestive tract bleeding after cerebral injury by positive gastric juice occult blood test in trial group, while 7 patients in control group. The occurrence rate of upper digestive tract bleeding of trial group was inferior to that of control group significantly( P 〈 0. 05 ). The healing rate of upper digestive tract bleeding of trial group was senoior to that of con- trol group significantly( P 〈0. 05). What's more, as for the days of healing upper digestive tract bleeding, the trial groups shortened the control group( P 〈 0. 05 ). Conclusion:After cerebral injury, nasogastric feeding of rhubarb powder early could decrease the occurrence rate of upper digestive tract bleeding, increase the healing rate of upper digestive tract bleeding, and shorten the days of healing it.
机构地区 文登整骨医院
出处 《辽宁中医杂志》 CAS 北大核心 2009年第2期241-242,共2页 Liaoning Journal of Traditional Chinese Medicine
关键词 重型颅脑损伤 上消化道出血 生大黄粉 中医药疗法 Severe cerebral injury Upper digestive tract bleeding Rhubarb Chinese herb treatment
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  • 1王茂德 刘亲勋 等.脑损伤后应激性溃疡患者血中三种激素的研究[J].中华神经外科杂志,1997,13(5):309-309.
  • 2孙星衍 孙冯翼辑.神农本草经[M].北京:科学技术文献出版社,1996.93.
  • 3梁秀兰,许庭生.大黄的现代临床医学研究及应用概述[J].中国社区医师,2002,18(11):6-7. 被引量:1

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