摘要
自身免疫性胰腺炎(AIP)是慢性胰腺炎中的一种特殊类型,好发于老年人,以血清中高IgG4水平、胰腺组织中有大量分泌IgG4的浆细胞浸润、胰腺肿大和胰管不规则狭窄为特征,甾类激素治疗有效,根据影像学、血清学、组织学和对甾类激素治疗的反应可作出诊断,但均无特异性。日本、韩国、美国相继制定了AIP的诊断标准,并提出了所谓的AIP亚洲诊断标准。目前我国AIP的病例报道不多,对该病的认识尚处于初始阶段,他国的诊断标准可作为我国AIP研究的良好借鉴。
Autoimmune pancreatitis (AIP) is a special type of chronic pancreatitis characterized by swelling of pancreas, irregular narrowing of pancreatic duct, high serum level of IgG4, infiltration of abundant IgG4 secreting plasma cells in pancreatic tissue, frequently seen in elderly and a good response to steroid therapy. The diagnosis of AIP is based on imageology, serology, histology and response to steroid therapy, but none is specific. Diagnostic criteria have been published consecutively in Japan, Korea and United States, and an 'Asia diagnostic criteria' has been suggested. As only a small number of cases of AIP have been reported in China since 2004, the study of AIP in China is just at the beginning and the diagnostic criteria of other countries will be the good references for the study of AIP in China.
出处
《胃肠病学》
2009年第1期2-3,共2页
Chinese Journal of Gastroenterology