摘要
目的探讨外伤性癫痫的致痫灶定位和手术方式选择。方法回顾性分析21例外伤性癫痫患者的临床资料，术前均行神经电生理学和神经影像学检查，结合临床表现综合定位致痫灶。采用病灶及周围皮层切除术12例，致痫灶切除加低功率皮层热灼术5例，前颞叶切除加杏仁核和大部分海马切除术3例，胼胝体切开术1例。结果经6个月～3年的随访，满意8例，显著改善6例，良好5例，效差2例，总有效率90％。结论外科手术是治疗难治性外伤性癫痫的一种重要方法，疗效取决于致痫灶的准确定位和多种手术方式的联合应用。
Objective To explore the localization of epileptogenic focus and select the appropriate surgical procedures for post-traumatic epilepsy. Methods The clinical data of 21 patients with post-traumatic epilepsy were studied retrospectively. Epileptogenic focus was located by comprehensively analyzing data of electro-neurophysiology, neurological imaging and clinical manifestation. Surgical proce- dures were performed in all patients, including resection of lesion and peripheral cortex in 12 patients, epileptogenic focus resection plus low power bipolar coagulation in five, anterior temporal lobectomy plus amygdalohippocampectomy in three and corpus callosotomy in one. Results All patients were followed up from 6 months to 3 years, which showed satisfactory outcome in eight patients, marked improvement in six, improvement in five and slight improvement in two. The total effective rate was 90%. Conclusions Surgical procedure is important for intractable post-traumatic epilepsy. The good efficacy depends on precise localization of epileptogenic focus and combined application of various surgical procedures.
出处
《中华创伤杂志》
CAS
CSCD
北大核心
2009年第2期116-119,共4页
Chinese Journal of Trauma
基金
河南省科技攻关计划资助项目（0524410048）
