摘要
目的寻找石见穿（Salvia chinensis Benth．）的活性成分，阐明其药效物质基础。方法采用硅胶柱色谱、凝胶柱色谱、十八烷基键合硅胶柱色谱分离；根据波谱数据分析鉴定化合物的结构。结果从石见穿中分离鉴定了9个化合物，分别为3一吲哚甲醛（indolyl-3-carbaldehyde，1）、芥子醛（sinapaldehyde，2）、松柏醛（coniferyl aldehyde，3）、丁香醛（syringaldehyde，4）、对羟基苯甲醛（p—hydroxybenzaldehyde，5）、香草醛（vanillin，6）、5-羟甲基糠醛（5-hydroxymethyl furaldehyde,7）、β-谷甾醇（β-sitosterol，8）、胡萝卜苷（daucosterol，9）。结论化合物1为首次从鼠尾草属植物中分离得到，化合物2—5、7为首次从石见穿中分离得到。
Objective To study the chemical constituents of the aerial parts of Salvia chinensis Benth. MethodsThe constituents were isolated by silica gel, ODS, Sephadex LH-20 column chromatography and the spectroscopic analysis methods were employed for the structural identification. Results Nine compounds were obtained and their structures were identified as indolyl-3-carbaldehyde （1）, sinapaldehyde （2）, coniferyl aldehyde（ 3 ）, syringaldehyde （ 4 ）, p-hydroxybenzaldehyde （ 5 ）, vanillin （ 6 ）, 5-hydroxymethyl furaldehyde （7） ,β-sitosterol（8 ）and daucosterol （9）. Conclusions Compound 1 is isolated from the genus Salvia for the first time. Compounds 2 -5 and 7 are isolated from Salvia chinensis for the first time.
出处
《沈阳药科大学学报》
CAS
CSCD
北大核心
2009年第2期110-111,156,共3页
Journal of Shenyang Pharmaceutical University
关键词
石见穿
化学成分
结构鉴定
Salvia chinensis Benth.
chemical constituent
structure identification
