摘要
目的探讨妊高征患者钙镁含量变化及硫酸镁的治疗机理。方法采用全自动生化分析仪测定３６例妊高征患者（妊高征组）外周血血浆和红细胞内的钙镁含量及硫酸镁治疗４小时时钙镁含量的变化，并以１４例正常妊娠妇女作对照（正常妊娠组）。结果中、重度妊高征患者血浆钙含量较对照组明显下降；红细胞内钙含量较对照组明显升高而镁含量明显下降。硫酸镁治疗４小时后，血浆、红细胞内镁值均较治疗前明显升高；血浆钙含量明显升高，而红细胞内钙含量明显降低。结论镁缺乏是妊高征患者体内离子紊乱的基础，硫酸镁能够改善这种紊乱，起到积极的治疗作用。
Objective To study the changes of calcium and magnesium levels in patients with pregnancy induced hypertension (PIH) and the therapeutic effect of magnesium sulfate (MgSO 4). Methods The calcium and magnesium levels in plasma and erythrocytes of 36 patients with PIH and 14 healthy gravidi in their late pregnancy were determined and the changes after 4 hours infusion of MgSO 4 as well.Result Plasma calcium decreased significantly in moderate and severe PIH patients,but calcium increased and magnesium decreased in their erythrocytes. After MgSO 4 infusion for PIH, magnesium levels in both plasma and erythrocytes increased, while calcium increased in plasma and decreased in erythrocyte to normal levels.Conclusion Magnesium deficiency is the basis of calcium and magnesium disturbances in PIH, and MgSO 4 treatment may improve the situation effectively.
出处
《中华妇产科杂志》
CAS
CSCD
北大核心
1998年第6期325-327,共3页
Chinese Journal of Obstetrics and Gynecology
关键词
妊娠高血压
药物疗法
硫酸镁
综合征
钙
镁
Pregnancy complications, cardiovascular Hypertension Magnesium Calcium Magnesium sulfate
