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小儿室缺伴主动脉瓣关闭不全的外科疗效分析 被引量:5

Ventricular Septal Defect Associated with Aortic Valve Insufficiency in Children:Analysis of Surgical Results and the Correlated Factors Affecting Prognosis
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摘要 总结小儿室间隔缺损(VSD)伴主动脉瓣关闭不全(AI)的外科治疗效果及其影响因素。随访82例VSD伴AI病儿的诊治和预后情况,并对多种影响因素进行t检验及多元线性回归分析。结果显示,小儿VSD合并AI发生率约为7.07%,其中干下型VSD伴AI占总数的19.58%;膜周型为4.18%。本组82例中64例单纯行VSD修补术,18例行VSD修补加主动脉瓣成形术。术后随访5个月~12年,无并发症,无近远期死亡,残余反流无1例较术前加重。结论:AI的程度、VSD类型及术前心胸比率等对选择手术方法有指导意义。 Aim:This retrospective study was conducted to evaluate the results of surgical treatment of ventricular septal defect(VSD)associated with aortic valve insufficiency(AI)in children and to explore the correlated factors affecting the prognosis.Clinical material and method:Of 880 patients with VSD treated in our hospital,68 patients(7.73%)were associated with AI.There were 38 boys and 30 girls with a mean age of 5.4 years (range,9 months to 12 years).Diagnosis was made by echocardiogram.According to Seller's classification,AI was mild in 55 patients,moderate in 11 and severe in 2.Supracristal defect was present in 41 patients and membranous defect in 27.Surgical repair of VSD was performed in 55 patients with mild AI,and combined closure of VSD and aortic valvaloplasty were done in 13 patients with moderate to severe AI.Results:There was no postoperative mortality.Postoperative residual AI was noticed in 10 patients(mild in 6 and moderate in 4).In the 6 month to 10 year follow up,there were no early or late deaths and no aggravation of residual AI.The mean cardiac to thoracic ratio was significantly reduced from 0.58±0.06 to 0.52±0.02(P<0.01).Postoperative echocardiogram study revealed that the mean pressure gradient across aortic valve markedly decreased from 67.5±16.9mmHg to 40.3±23.2mmHg(P<0.01).Conclusion:The results of this study suggested that severity of AI and type of VSD,affect the choice of surgical technique and effectiveness of aortic valvuloplasty.
出处 《中华胸心血管外科杂志》 CSCD 北大核心 1998年第2期71-73,共3页 Chinese Journal of Thoracic and Cardiovascular Surgery
关键词 室间隔缺损 主动脉瓣 关闭不全 儿童 外科手术 Ventricular septal defect Aortic insufficiency Valvuloplasty
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同被引文献19

  • 1梅举,张宝仁,邹良健,徐志云,于伟勇,王志农,丁芳宝,赵枫.主动脉瓣关闭不全成形术的临床研究[J].第二军医大学学报,2005,26(12):1436-1437. 被引量:7
  • 2李守先 徐光亚.实用心脏外科学[M].济南:山东科学出版社,1999..
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  • 5Okita Y, Miki S, Kusuhhara K, et al. Long-term results of aortic valvuloplasty for aortic regurgitation associated with ventricular septal defect. J Thorac Cardiovasc Surg, 1988,96:769 - 774.
  • 6Trusler GA, Williams WG, Smallhom JF, et al. Late results after repair of aortic insufficiency associated with ventricular septal defect. J Thorac Cardiovasc Surg, 1992,103:276 - 281.
  • 7Isihikawa S, Morishita Y, Sato Y, et al. Frequency and operative correction of aortic insufficiency associated with ventricular septal defect. Ann Thorac Surg, 1994, 57:996 -998.
  • 8Tohyama K, Satomi G, Momma K. Aortic valve prolapse and aortic regurgitation associated with subpulmonic ventricular septal defect. Am J Cardiol. 1997, 79:1285 - 1289.
  • 9Konno S,Imai Y,Lida Y,et al.A new method for prosthetic valve replacement in congenital aortic stenosis associated with hypoplasia of the aortic valve ring.J Thorac Cardiovasc Surg,1975,70:909-917.
  • 10Brauner R,Birk E,Sahar G,et al.Surgical management of ventricular septal defect with aortic valve prolapse:clinical considerations and results.Eur J Cardiothorac Surg,1995,9(6):315-319.

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