摘要
目的考察盐酸氨甲苯酸注射液与盐酸莫西沙星氯化钠注射液配伍的稳定性。方法在25℃和37℃下8h内,采用紫外分光光度法测定氨甲苯酸(4.8mg/L)与莫西沙星(9.6mg/L)配伍后的含量,并测定pH值,观察外观、性状变化。结果两药配伍后8h内外观、pH值无明显变化,但在4h时氨甲苯酸的含量明显下降。结论盐酸莫西沙星氯化钠注射液与氨甲苯酸注射液在2h内可以配伍使用。
Objective To study the compatibility of Aminomethylbenzoic Acid Injection in Moxifloxacin Hydrochloride and Sodium Chloride Injection. Methods At 25℃ and 37℃ within 8 h, the ultraviolet spectrophotometry was tised to study the change of content after the combination of aminomethylbenzoic acid （4.8 mg/L） and moxifloxacin （9.6 mg/L）. The change of the liquid appearance and its pH were observed. Results No significant change was seen in appearance and pH value after 8 h of mixing of the two agents. But after 4 h of mixing, the content of aminomethylbenzoic acid obviously dropped. Conclusion The compatibility of Aminomethylbenzoic Acid Injection with Moxifloxacin Hydrochloride and Sodium Chloride Injection can be used within 2 h.
出处
《中国药业》
CAS
2009年第3期7-8,共2页
China Pharmaceuticals
关键词
氨甲苯酸
莫西沙星
配伍
稳定性
紫外分光光度法
aminomethylbenzoic acid
moxifloxacin
compatibility
stability
UV ectrophotometry
