摘要
目的:观察索他洛尔治疗阵发性心房颤动的疗效。方法:将121例阵发性心房颤动患者随机分成两组,索他洛尔治疗组61例,普罗帕酮组60例,疗程4周。结果:索他洛尔治疗组有效率75%,普罗帕酮组有效率63%,两者有显著差异(P<0.05)。不良反应发生率,索他洛尔治疗组为8.2%;普罗帕酮组为15.0%,与心脏有关的不良反应发生率为8.3%。随访期间未发生严重心脏事件。结论:索他洛尔治疗阵发性心房颤动疗效优于普罗帕酮。
Objective：To observe the efficacy of sotalol in the treatment of paroxysmal atrial fibrillation. Methods：The total of 121 cases of paroxysmal atrial fibrillation were randomly divided into two groups, 61 cases were in sotalol group, while 60 cases were in propafenone group. The course of treatment was 4 weeks. Results：The effective rates in sotalol group and propafenone group were 75% and 63%, respectively. There were significant differences between two groups （P〈0.05）. The adverse reaction rates in sotalol group and propafenone group were 8.2% and 15.0%, respectively. The adverse reaction rate associated with the heart was 8.3 % in propafenone group. No severe cardiac accidents happened in two groups during the follow-up survey period. Conclusion： The therapeutic effect of sotalol in the treatment of paroxysmal atrial fibrillation is better than propafenone.
出处
《中国临床医学》
北大核心
2008年第6期766-767,共2页
Chinese Journal of Clinical Medicine
