摘要
目的评价脂肪肝内转移瘤的影像学表现及各种检查方法(重点为CT)的价值。方法脂肪肝内转移瘤9例,随诊3~13个月临床证实。原发肿瘤为乳腺癌6例,卵巢癌、恶性黑色素瘤、结肠癌各1例。CT扫描9例19次,B超扫描9例20次。MRI4例4次,血管造影2例6次。结果B超扫描2例次在中重度脂肪肝漏诊转移瘤。CT平扫根据肝密度低于脾,并低于、等于、高于肝内血管影,分为重度、中度、轻度脂肪肝。瘤灶分别呈高密度(重度),高、等、低密度(中度)和低密度(轻度脂肪肝)。增强后,中、重度脂肪肝背景瘤灶均呈高密度。4例瘤灶密度不均。平扫4例瘤灶周围有2~6mm高密度晕环。MRI的SE序列T1W为低信号,T2W为高信号,反相位(opposed-phase)为较高信号。结论脂肪肝内转移瘤的影像学表现较为复杂,与脂肪浸润程度密切相关。CT平扫时,中度脂肪肝因等密度易漏诊转移瘤。见有全周或半周较高密度环或密度不均者,应警惕肝转移瘤的可能,必须加作增强扫描以免漏诊。细致的MRI检查有助于检出转移瘤。
Objective To evaluate the manifestations of tumors metastasized in fatty liver and the value of various imaging modalities, especially CT. Methods Nine cases of tumors metastasized in fatty liver were proved by clinical follow up for 3~13 months. The primary neoplasms were breast carcinoma in 6 cases; ovarian carcinoma,malignant melanoma and colon carcinoma, one case for each. All had CT(19 episodes) and ultrasonography (US, 20 episodes). Four cases had MRI and 2 cases had DSA. Results Liver metastatic lesions were missed by US in 2 cases with moderate to marked fatty liver. On CT without contrast administrations, fatty liver was divided into marked、 moderate and mild degree according to the density of hepatic parenchyma which was lower than that of the spleen; lower and higher than or equal to that of the intrahepa tic blood vessels. Depending on the degree of fat infiltration(FI), the density of the metastatic lesions was high when FI was marked and low when FI was mild. However, when FI was moderate, the density of the metastatic lesions varied, being high, equal or low. On enhanced CT, all of the lesions were enhanced with moderate to marked fatty liver background. Lesions were heterogeneous in 4 cases. On plain CT, metastatic lesions had high density rim, 2~6mm in width in 4 cases. In SE sequence of MRI, metastatic lesions were hypointense on T 1W and hyperintense on T 2W, and moderately hyperintense on opposed phase. Conclusion Tumors metastasized in fatty liver show a broad spectrum of image manifestations. They are related to the degree of fat infiltration. On plain CT, isodense lesions are easily escaped detection when moderate degree of fatty liver is present. Contrast adminstrations is mandatory. Liver metastases is suggested if a lesion is found with hyperattenuating rim on plain CT, or appears heterogeneous after enhancement. MRI is of diagnostic help.
出处
《中华肿瘤杂志》
CAS
CSCD
北大核心
1998年第2期132-134,共3页
Chinese Journal of Oncology
关键词
肝肿瘤
脂肪肝
CT
诊断
Liver neoplasm/radiography Liver neoplasms/secondary Fatty liver Tomography,X ray computed