摘要
目的:研究急性心肌梗死(AMI)静脉溶栓后迟发性ST段再抬高的临床意义。方法:入选发病12小时之内行溶栓治疗成功的AMI患者180例,根据溶栓12小时后ST段是否再抬高分为A、B两组,监测CPK、CK-MB峰值及峰值时间,记录有无再灌注心律失常、心力衰竭,1周、1月、3月及6月各随访1次,复查心脏超声。结果:A组前壁心肌梗死的发生率,合并高血压、糖尿病、血脂紊乱者以及CPK、CK- MB峰值显著高于B组,CPK、CK-MB峰值时间较B组提前程度小,心力衰竭、室壁瘤发生率及死亡率均显著高于B组(P均<0.05)。结论: AMI溶栓成功后迟发性ST段再抬高者心力衰竭、室壁瘤发生率高,预后相对差。
Objective： To study the clinical significance of delayed ST segment re-elevation in AMI patients with thrombolytic therapy. Methods： 180 AMI patients who onsetted within 12 hours and thrombolysis successful were enrolled. The patients were divided into A and B group according whether ST segment re-elevation after 12 hours of thrombolytic therapy. Peak value and time of CPK, CK-MB were recorded： repeffusion arrhythmia and heart failure were recorded; the patients were followed up at 1 week, 1, 3 and 6 month respectively, and UCG was rechecked every time. Results： Compared with B group, rate of anterior myocardial infarction, heart failure and ventricular aneurysm, peak value of CPK and CK-MB, and mortality were significantly higher in A group （P〈O.05）; the peak time of CPK and CK-MB was relatively longer; co-existed diseases, such as hypertension, diabetes and lipid disorders were significantly higher in A grocp （P〈0.05）. Conclusion： The incidence of heart failure and ventricular aneurysm increase in AMI patients with delayed ST segment re-elevation after thrombolysis, and the prognosis was relatively worse.
出处
《中国医药导刊》
2008年第9期1332-1333,共2页
Chinese Journal of Medicinal Guide
关键词
急中牛心肌梗死
溶栓
迟发性ST段再抬高
Acute myocardial infarction
Thrombolysis
Delayed ST segment re-raise
