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甲磺酸罗哌卡因与盐酸罗哌卡因用于腋路臂丛神经阻滞的对比研究 被引量:8

Comparative study of Ropivacaine Mesylate and Ropivacaine Hydrochloride for axillary brachial plexus block
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摘要 目的:比较甲磺酸罗哌卡因与盐酸罗哌卡因用于腋路臂丛神经阻滞的有效性和安全性。方法:48例ASAⅠ~Ⅱ级择期上肢手术患者随机分为0.5%盐酸罗哌卡因组(A组)和0.596%甲磺酸罗哌卡因组(B组)。每组24例,两组患者均行腋路臂丛神经阻滞,观察感觉与运动神经阻滞起效时间、持续时间及不良反应,评价麻醉效果。结果:在感觉与运动神经阻滞的起效时间、持续时间及不良反应方面,0.596%甲磺酸罗哌卡因与0.5%盐酸罗哌卡因未见明显差异。结论:0.596%甲磺酸罗哌卡因与0.5%盐酸罗哌卡因应用于腋路臂丛神经阻滞,具有相似的有效性和安全性。 Objective: To compare the efficacy and safety of Ropivacaine Mesylate and Ropivacaine Hydrochloride for axillary brachial plexus block. Methods: 48 ASA Ⅰ or Ⅱ patients scheduled for upper extremity surgery were randomly divided into two groups: 0.5% Ropivacaine Hydrochloride group (group A) and 0.596% Ropivacainc Mesylate group (group B), with 24 patients in each group. All patients were performed with axillary brachial plexus block. Then the initiating time, lasting time of sensory and motor block as well as the adverse reaction were observed, and the anesthetic effect was evaluated. Results: No significant difference of the initiating or lasting time, or even the adverse reaction of sensory and motor block was observed between the two groups. Conclusion: 0.5% Ropivacaine Hydrochloride and 0.596% Ropivaeainc Mesytate have similar efficacy and safety in the application of axillary brachial plexus block.
出处 《中国医药导报》 CAS 2009年第1期67-68,共2页 China Medical Herald
关键词 甲磺酸罗哌卡因 盐酸罗哌卡因 腋路臂丛神经阻滞 Ropivacaine Mesylate Ropivacaine Hydrochloride Axillary brachial plexus block
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  • 1朱波,徐建青,叶铁虎,任洪智,黄宇光,罗爱伦.腹式子宫切除术后甲磺酸罗哌卡因与盐酸罗哌卡因硬膜外病人自控镇痛的比较[J].中华麻醉学杂志,2005,25(8):572-575. 被引量:42
  • 2褚淑娟,张小洺,姚尚龙.硬膜外甲磺酸罗比卡因复合吗啡应用于妇科术后镇痛的观察[J].临床麻醉学杂志,2006,22(6):422-423. 被引量:15
  • 3薛晓东,张晋东,夏舒萌,范勤,纪钧,宋志鸿.甲磺酸罗哌卡因与盐酸罗哌卡因在硬膜外麻醉中的比较[J].临床麻醉学杂志,2007,23(4):346-346. 被引量:5
  • 4Liu BG, Zhuang XL, Li ST, et al. The effect of ropivacaine on sodi um currents in dorsal horn neurons of neonatal rats [ J ]. Anesth & Analg, 2000, 90(5) :1034 -39.
  • 5Santos AC, De Armas PI. Systemic toxicity of levobupivacine, bupivacaine, and ropivacaine during continuous intravenous infusion to nonpregnant and pregnant ewes[ J]. Anesthesiology, 2001, 95 (5): 1256 -61.
  • 6Proter JM, Markos F, Snow HM, et al. Effect of respiratory and metabolic PH changes and hypoxia on ropivacaine-induced cardiotoxicity in dogs [ J ]. British Journal of Anaesthesiology, 2000, 84 (1): 92 -97.
  • 7Stefanie R, Pascal L,Gilles, et al. High-performance liquid chromatographic determination of ropivacaine, 3-hydroxy-ropivacaine, 4 -hydroxy-ropivacaine and 2,6-pipecoloxylidide in plasma [ J ]. J Chromatogr B, 1998,719:239 - 44.
  • 8Haiidin M, Brredberg E, Angelin B, et al. Metabolism and excretion of ropivacaine in humans [ J ]. Drug Metab Dispos, 1996,24: 962 - 68.
  • 9陈伯銮.局部麻醉药.见:刘俊杰,赵俊,主编.现代麻醉学.第2版,北京:人民卫生出版社,1997.297-313.
  • 10Lacassie HJ,Columb MO,Lacassie HP,et al. The relative motor blocking potencies of epidural bupivacaine and ropivacaine in labor. Anesth Analg, 2002,95: 204-208.

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