摘要
目的探讨胰岛素抵抗(IR)检测在诊治心血管疾病中的应用。方法分别对86例高血压和冠心病患者及36例对照组健康体检者进行三酰甘油(TG)、总胆固醇(TC)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)、空腹血糖(FBG)、空腹血胰岛素(FINS)、C肽(CP)等指标的测定,并计算胰岛素抵抗指数(IRI)。结果3组高血压冠心病患者TG、TC、HDL-C、及LDL-C水平分别与对照组比较,差异有统计学意义(P<0.05);FINS、CP、IRI水平与对照组比较明显升高,差异也有统计学意义(P<0.01)。结论心血管疾病患者中,IRI明显升高,与高血压冠心病密切相关,是冠心病和高血压的一个独立危险因素。
Objective To explore the application of insulin resistance （IR） in diagnosis and treatment of cardi ovascular diseases （CAD）. Methods The levels of triglyceride （TG） ,total cholesterol （TC） ,high density lipoprotein cholesterol （ HDL-C）, low density lipoprotein cholesterol （LDL-C）, fasting blood insulin （FINS）, C-peptide （CP） and fasting blood glucose （FBG） were measured in 86 patients with coronary heart disease （CHD） and hypertension and 36 healthy controls,and then insulin resistance index （IRI） was calculated. Results There were statistical differences in levels of TG,TC,HDL-C and LDL-C between CAD group and healthy control group （P〈0. 05）; the levels of FINS,CP and IRI in CAD group were significantly higher lhan those in healthy control group （P〈0.01）. Conclusion As a dependent risk factor for cardiovascular diseases, significantly increasing IRI is associated with development of coronary heart disease and hypertension.
出处
《检验医学与临床》
CAS
2009年第1期13-14,共2页
Laboratory Medicine and Clinic
关键词
胰岛素抵抗
糖尿病
高血压
冠心病
insulin resistance
diabetes mellitus
hypertension
coronary heart disease
