摘要
目的探讨雷公藤左旋咪唑混悬液对皮肤表皮内Ｌａｎｇｅｒｈａｎｓ＇ｃｅｌ（ＬＣ）的影响。方法室温下经雷公藤左旋咪唑混悬液浸泡人和大鼠皮片３ｈ，采用ＡＴＰ酶法显示表皮片中的ＬＣ。结果显微镜下见：ＬＣ数量减少，胞体浓缩或崩溃变形，树突状结构明显减少。ＬＣ数减少与生理盐水对照有显著性差异。结论雷公藤左旋咪唑混悬液体外浸泡皮片对表皮内ＬＣ的数量和结构均有影响，从而使ＬＣ功能受抑，同种异体皮肤移植排斥延迟。
Objective In order to find the intermingled levamisole and tripterygium solutions effect on skin Langerhans cells(LC). Method The ATPase was used as dying method to show LC. Immersing time was 3 h at room temperature. Results The study showed skin pieces freated with the intermingled levamisole and tripterygium solution had fewer and damaged LC compared with control group. Conclusions The solution could depress LC and delay skin allograft.
出处
《安徽医科大学学报》
CAS
1998年第1期23-25,共3页
Acta Universitatis Medicinalis Anhui
关键词
雷公藤
左旋咪唑
皮肤移植
移植物排斥
LC
eSH tripterygium wilford Ⅱ/pharmacol
levamisole/pharmacol
Langerhans cells/drug eff
skin transplantation
graft rejection/drug eff
