摘要
目的观察全葡萄膜炎的荧光素眼底血管造影(FFA)及吲哚菁绿血管造影(ICGA)特征。方法对22例(22只眼)全葡萄膜炎患者的28只眼按常规方法做 FFA 检查。其中4例(8只眼)做 ICGA 检查。结果 16例活动性病变的 FFA 均出现视盘及附近视网膜高荧渗漏,其中4例(6只眼)视网膜血管充盈延迟,狭窄或闭塞,管壁染色渗漏为主,6例(9只眼)毛细血管荧光素渗漏,7只眼视网膜色素上皮荧光素渗漏;6只眼黄斑点状荧光素渗漏,4例(6只眼)黄斑囊样水肿,3例(4只眼)伴视网膜出血及棉绒斑。6例(6只眼)陈旧性全葡萄膜炎见视网膜弥漫斑驳样荧光部分合并小的遮蔽荧光。4例吲哚菁绿造影中1例特发性全葡萄膜炎表现为脉络膜毛细血管扩张及高荧光,1例 VKH 早期脉络膜血管无异常,后期脉络膜不均匀的荧光渗漏。1例白塞病2只眼表现为脉络膜毛细血管充盈不良、低荧光遮蔽,1例白塞病患者双眼脉络膜及血管未见异常。结论全葡萄膜炎的 FFA 特征为视盘、视网膜色素上皮、视网膜血管和黄斑出现不同程度的荧光素渗漏。ICGA 以脉络膜的低荧光和(或)高荧光表现为主、早期脉络膜血管可以无变化。FFA 及 ICCG 能客观地反映葡萄膜炎对视网膜组织的损害,对确定葡萄膜炎的类型及病程提供诊断和治疗依据。
Objective To investigate the characteristics of panuveitis by fundus fluorescein angiography （FFA） and isochronous indooyanine green （ 1CGA ）. Methods 22 panuveitis patients Including 28 eyes were examined by FFA. 4 Patients 8 eyes were examined by 1CGA. Results Optic disk and nearby retina of 22 eyes appeared sheet-like leakage of fluorescein, the retinal vessel of 6 eyes in 4 patients were delayed filling, the vessel were stenosis or occlusion and leakage of fluorescein. In 6 patients 9 eyes the capillary were dilated at the venous phase , the leakage of fluorescein was seen at the retinal pigment epithelium in 7 eyes , the macular of 6 eyes appeared dot-like leakage of fluorescein . 6 eyes with the cystoid macular edema. There were retinal hemorrhage and retinal cotton wool spots in 4 eyes. There were geographic pattern leakage of fluorescein and company with small blocked fluorescence in 6 patientswith inactivity changes. The hypofluorescense of ICGA was prominent in 1 behcets patients＇ 2 eyes and the capillary of choroids were delayed filling. The capillary of choroids were dilated in leye and the ICGA showed hyperfluorescense. The capillary of choroids were normal in the early stage and show inhomogeneity leakage spots in the later stage in 1 VKH patient （ 2eyes ） . The Results of ICCG showed nothing abnormal in 1 behcets patient （2 eyes）. Conclusion These characteristics of ICGA and FFA suggest that there are different damages to the retina in all kinds of panuveitis. Optic disk , RPE, retinal vessel and the macular have different extent of fluorescein leakage. The hypofluorescense or hyperfluorescene of ICGA is prominent. There are no changes of choroids vessels in the early stage in some cases. It is important to differ these changes prompting some special panuveitis by FFA and ICGA. It also can offer some objective evidence for diagonosis and treatment cf panuveitiso
出处
《临床眼科杂志》
2008年第6期511-514,共4页
Journal of Clinical Ophthalmology
关键词
全葡萄膜炎
荧光素眼底血管造影
吲哚菁绿血管造影
Panuveitis
Fundus fluorescein angiography
Isochronous indocyanine green angiography
