摘要
目的探讨胶质瘤术后癫痫发生的影响因素。方法回顾性分析接受开颅手术且资料完整胶质瘤病例258例,以性别、年龄、主要症状、阳性体征、术前癫痫病史、癫痫时间、病变部位、手术入路、皮质牵拉伤、动静脉损伤、肿瘤切除程度、术后水肿、病理性质、病变复发、手术次数、放射治疗等16项可能的影响因素为自变量,设定术后"发生癫痫"为因变量,使用logistic回归分析研究相关的影响因素。结果术前癫痫史、手术入路、术后水肿、病理性质、病变复发等5个因素为胶质瘤术后癫痫发生的影响因素。结论胶质瘤术后癫痫的发生影响病人生活质量,针对癫痫发生影响因素的防治,有望减少胶质瘤术后癫痫发生。
Objective To explore the predisposing factors for postoperative epilepsy in patients with gliomas. Methods A total of 258 glioma patients with complete clinical data receiving cranial surgeries were analyzed retrospectively. With gender, age, predominant symptoms, positive signs, history of preoperative epilepsy, time of epilepsy onset, tumor location, surgical approaches, cortical injury, arterial and venous injury, scope of tumor resection, postoperative edema, tumor pathology, tumor recurrence, number of operation, radiation therapy as the independent variables, the occurrence of postoperative epilepsy was analyzed as the dependent variable using logistic regression to identify the risk factors for postoperative epilepsy. Results History of preoperative epilepsy, surgical approaches, postoperative edema, tumor pathology and tumor recurrence were identified as the risk factors for postoperative epilepsy in glioma patients. Conclusion Postoperative epilepsy severely affected the quality of life ofglioma patients, and rigorous treatment targeting the risk factors may decrease the occurrence of postoperative epilepsy.
出处
《南方医科大学学报》
CAS
CSCD
北大核心
2008年第12期2233-2234,2238,共3页
Journal of Southern Medical University
关键词
胶质瘤
癫痫
影响因素
glioma
epilepsy
related factors
