期刊文献+

枸橼酸莫沙必利对成人心电图QT间期的影响 被引量:3

暂未订购
导出
摘要 目的评价枸橼酸莫沙必利对成人心电图QT间期的影响。方法随机抽取患者有慢性胃炎、功能性消化不良、反流性食管炎及胃瘫等并排除心律失常的成人患者80例,均餐前口服枸橼酸莫沙必利5mg,3次/d,连续2周,观察并记录所有患者服用前、服用2周后的心电图QT间期。结果80例患者心电图QT间期均在正常值范围,服药前后患者心电图QT间期分别为(0.40±0.32)ms、(0.40±0.31)ms。服药前后QT间期变化差异无统计学意义(P=0.949)。服药期间亦未见其他严重不良反应。
出处 《中国厂矿医学》 2008年第6期663-663,共1页 Chinese Medicine of Factory and Mine
  • 相关文献

参考文献10

  • 1Yoshida N. Pharmacololglcal effects of the gastroprokinetic agent mosapride citrate[ J]. Nippon Yakurigaku Zasshi, 1999,113:299 - 307.
  • 2Farrington E. Cardiac toxicity with cisapride[J]. Padiatr Nuts,1996,22:256.
  • 3Dan M. Roden,李辉.药物导致的QT间期延长[J].中国心血管杂志,2008,13(1):74-75. 被引量:5
  • 4Yoshida N, Omoya H, Oka M, et al. AS-4370, a novel gatrokinetie a-gent free of dopamine D2 receptor antagonist properties [ J ]. Arch Int Pharmaeodyn Ther, 1989,300:51 - 67.
  • 5Makimoto N, Sakurai-Yamashita Y, Furuiehi A, et al. In vivo assessmerit of acceleration of motor activity associated with aeetylcholine release via 5-hydroxytryptamine 4 receptor in dog intestine [ J ]. Jpn J Pharmacol,2002,90:28 - 35.
  • 6Carlsson L, Amos GL, Andersson B, et al. Electrophysiological characterization of the prokinetic agents cisapride and mosapride in vivo and in vitro: implications for proarrhythmic potential? [ J]. J Pharmacol Exp Ther, 1997,282:220 - 227.
  • 7Kii Y, ho T. Effects of 5-HT4-receptor agonists, cisapride, mosapride citrate,and zacopridc,on cardiac action potentials on guinea pig isola- ted papillary museles[J]. J Cardiovase Pharmacol, 1997,29:670.
  • 8Katoh T, Saitoh H, Ohno N, et al. Drug Interaction between mosapride and erythromycin without electrocardiographic changes [ J ]. Jpn Heart J ,2003,44:225 - 234.
  • 9Endo J,Nomura M, Morishita S,et al. Influence of mospride citrate on gastric motility and autonomic nervous function:evaluation by spectral analyses of heart rate and blood pressure variabilities and electrogas-trography[ J ]. J Gastroenterol,2002,37:888 - 895.
  • 10Ruth M, Hamelin B, RShss K, et al. The effect of mosapride, a novel prokinetic ,on acid reflux variables in patients with gastroesophageal reflux disease[ J ]. Aliment Pharmacol Ther, 1998,12:35 - 40.

共引文献4

同被引文献23

二级引证文献19

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部