摘要
目的探讨腰椎人工髓核植入对邻近节段腰椎稳定性的生物力学影响。方法新鲜小牛腰椎脊柱标本8具,分别制备成正常组、腰椎髓核摘除组、人工髓核植入组模型,自体对照,分别记录髓核摘除后、人工髓核植入与正常组对腰椎邻近节段的应变及应力改变,以此评估其对腰椎生物力学稳定性的影响。结果单纯髓核摘除术后病变节段上方相邻节段椎体的应变明显下降(P<0.05);人工髓核植入后其相应部位的应变与正常相比仅有数值上的增加,无统计学意义(P>0.05);髓核摘除后上位节段邻椎的椎体、椎间盘的应力均有增加,髓核植入后其应力基本恢复正常。结论人工髓核植入能有效维持上位相邻腰椎椎间盘、椎体的正常应力以及应变水平,维持脊柱正常的生物力学,延缓上位邻近椎体、椎间盘的退变。
Objective To evaluate the biomechanical changes on the annuli fibrosis and vertibral body of the adjacent segments on the condition of PDN implantation. Methods To measture the variety of stress of 8 model made of fresh cow lumbar spine on three conditions： normal, nucleotomy, PDN implantation. Each group was measured under the loading of states of vertical compression , flexion , extention, and lateral bending. Results Afer nucleotomy the stress of the adjacent segments decreased significantly while it increased after implantation of PDN. The pressure of vertebral body and intervertibral disc increased after nucleolomy. Conclusions PDN implantation can correct the biomechanical disorders of spine after nucleotomy and decrease the degeneration of adjacent vertebre.
出处
《浙江临床医学》
2008年第12期1536-1538,共3页
Zhejiang Clinical Medical Journal
基金
嘉兴市科技计划项目(2006AY2030)
关键词
腰椎
人工髓核
邻椎病
生物力学
Lumbar PDN Fixation of lumbar Biomechanics Faced joints
