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2型糖尿病与代谢综合征及二者相关性临床分析 被引量:2

Clinical analysis of correlation of metabolic syndrome with type 2 diabetes
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摘要 目的探讨2型糖尿病(T2DM)住院患者代谢综合症(MS)的状况;T2DM、T2DM慢性并发症与代谢综合征的相关性。方法选取于2007~2008年符合2型糖尿病诊断的住院患者200例,统计糖尿病慢性并发症和MS患病率,并按是否合并MS分组,同时收集健康体检者资料200例,分别测定身高、体重、血压、血糖、血脂、尿酸、尿白蛋白等指标,共收集400例的资料,以判断MS患病率及二者相关性。结果T2DM住院患者合并代谢综合征的比例是40%,合并3项代谢异常的比例是26%,合并4项代谢异常的比例是14%,与健康对照组比较有统计学差异(P<0.01);合并MS的T2DM患者发生大血管并发症的比例是25%,显著高于无合并MS组(P<0.05)。结论①T2DM住院患者合并MS的比例比健康对照组显著升高;②T2DM合并MS组比无合并MS组发生大血管病变的比例显著升高;应对T2DM患者早期给予针对性干预,包括生活方式干预,除血糖达标外,同时针对各种心血管危险因素治疗,以预防临床心血管疾病的发生及再发生的目标。 Objective To investigate the incidence of metabolic syndrome (MS)in tyupe 2 diabetic patients and their correlation. Methods All 200 type 2 diabetic inpatients in deparment of endocrinology of Jiangmem Central Hospital were included in this observation from 2007 to 2008 and another 200 healthy control were selected.The incidence of type 2 daibetes with chronic complications with/or without metabolic syndrome, their correlaton were analyzed. In addition, the height,weight and blood pressure of the patients were measured, the levels of blood glucose,total cholesterol, triglyceride, HDL-C and LDL-C were determined. Results There were 40% of the type 2 diabetic patients were complicated with MS, 26% and 14% of them compheated with 3 and 4 abnormal metabolic indicators,showing significant differences as compared to the healthy controls (P〈0.01); The prevalences of macrovascular complications were significantly highter in those with MS than those without MS (P〈0.05). Conclusion The prevalences of MS in type 2 diabetic patient is higher than in that of the healthy controls. The prevalence of diabetic chronic complications is significantly higher in those with MS than in those without MS.
出处 《中国热带医学》 CAS 2009年第1期65-66,187,共3页 China Tropical Medicine
关键词 代谢综合征 糖尿病 并发症 患病率 Metabolic syndrome Diabetes mellitus Complications Prevalence
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