摘要
目的评估供肝手术方式对供体的安全性。方法86例供体接受了活体肝移植供肝手术:左叶供肝58例(A组);右叶供肝28例(B组)。收集并分析供者住院及出院1、3、6个月CT、B超及肝功能随访资料。结果86例供体手术顺利,康复出院。A、B两组平均手术时间[(7.40±0.88)h vs.(8.00±0.84)h]、平均失血量[(457.41±40.74)ml vs.(518.96±40.74)ml]和平均术后住院时间[(18.62±0.92)d vs.(10.16±0.99)d]均有统计学差异(P<0.05)。两组供体肝功能指标可有轻度波动,1周内均恢复正常。CT显示供肝者残留肝恢复至(或超过)正常肝体积的时间:A组6～11个月,B组10～14个月(P<0.05)。A、B组术后恢复期分别有30.7%和32.3%供肝者出现一过性腹部不适、疼痛等;A、B组术后8个月分别有88.5%和85.6%的供肝者恢复术前工作或劳动。结论健康成人捐献部分肝脏是安全、可行的。
Objective To evaluate the safety of donor in living donor liver transplantation.Methods Eighty-six patients as the donors received partial hepatectomy of the left lobe in 58 cases（group A） and the right lobe in 28 cases（group B）.The data of in-hospital and 6-month out-hospital follow-up including liver function,B-ultrosound and CT scan were collcted and analyzed.Results All donors recovered uneventfully in hospital.There were significant differences in average time of hepatectomy [（7.40±0.88）h vs.（8.00±0.84）h], blood loss [（457.41±40.74）ml vs.（518.96±40.74）ml] and hospital stay [（18.62±0.92）d vs.（10.16±0.99）d] between group A and B（P〈0.05）.The percentage of patients complained of transient abdominal uncomfortableness or pain in the early time of discharge was 30.7% in group A and 32.3% in group B.The CT follow-up showed that the time for donors′ remnant livers to reach or exceed the original volume was 6 to 11 months in group A and 10 to 14 months in group B（P〈0.05）.Eight months after operation,88.5% of group A and 85.6% of group B went to work as before.Conclusion It is safe and feasible for healthy adults to donate partial liver for living donor liver transplantation.
出处
《江苏医药》
CAS
CSCD
北大核心
2008年第12期1210-1211,共2页
Jiangsu Medical Journal
关键词
活体肝移植
供体
Living donor liver transplantation
Donor
