摘要
目的探讨3.0T磁共振(MRI)三维容积内插屏气检查(3D—VIBE)序列动态增强扫描对小肝癌的检出率,并评价其在小肝癌定性诊断中的价值。方法回顾性分析经临床手术及病理学检查证实的61例小肝癌患者的影像学资料,用3.0T磁共振扫描仪进行平扫及3D—VIBE序列动态增强扫描。分析病灶在3D—VIBE序列动态增强扫描各个时相的信号特点及强化特征,评价各平扫及增强序列对病灶的检出率及定性诊断价值。结果61例患者手术共发现66个病灶,49个病灶见假包膜形成。T1加权成像(T1WI)发现病灶43个(65.15%),19个(38.78%)见假包膜。T2加权成像(T2WI)发现病灶53个(80.30%)。3DVIBE序列动态增强扫描共发现65个病灶(98.48%),35个(71.43%)见假包膜。3种不同序列对病灶检出率的差异具有统计学意义(Χ^2=24.197,P〈0.05)。平扫(T1WI+T2WI)与3D—VIBE序列动态增强扫描对病灶的定性准确率的差异也具有统计学意义(Χ^2=66,P〈0.05)。结论3.0TMRI3D—VIBE序列动态增强扫描的扫描速度快,可清楚显示动脉期、门静脉期及实质期等各个时相的特点,这不仅有利于发现平扫所不能发现的小病灶,而且可以通过绘制时间-信号强度曲线协助诊断。对肝癌癌灶的检出及鉴别诊断具有重要价值。
Objectives To investigate the detection rate of small hepatocellular carcinomas using 3.0T MRI 3D-volumetric interpolated breath-hold examination(VIBE)sequence dynamic contrast-enhanced scan,and to evaluate its application in the diagnosis of small hepatocellular carcinomas.Methods Imaging data of 61 cases of small hepatocellular carcinomas obtained using a 3.0 T Siemens Magnetom Trio Tim magnetic resonance scanner for plain scan and multi-phase dynamic contrast-enhanced scans of three-dimensional volumetric interpolated breath-hold examination(3D-VIBE)were retrospectively analyzed with reference to their pathological diagnoses.The signal and enhanced features and the detection rates of the tumors in different phases of examination were analyzed.Results Sixty-six lesions were detected in the livers of the 61 patients by pathological examinations,of which 49 had pseudocapsule formation.In their T1WI plain scanning,43(65.15%)lesions were found,of which pseudocapsules were found in 19(38.78%).In their T2WI imaging,53(80.30%)lesions were found.In dynamic enhanced 3D-VIBE sequence,65(98.48%)lesions were found,of which 35(71.43%)were found with pseudocapsules.The sizes of the carcinomas ranged from 0.8 to 3.0cm,2.1 cm on the average.The results of statistical analysis for the detection rates of the cancers of the three different sequences were significantly different(Χ^2=24.197,P〈0.05).The differences of qualitative accuracy obtained by plain scan(TIWI+T2WI)and 3D-VIBE sequence were significantly different(Χ^2=66,P〈0.05).Conclusion 3.0 T MRI 3D-VIBE sequence dynamic contrast-enhanced scan is high-speed and can clearly demonstrate the arterial phase,the portal venous phase and the parenchymal phase images.It not only can find small lesions which can not bc found with a plain scan,but also can assist diagnosis through a time-intensity curve.It is of great value for detection and differential diagnosis of small hcpatocellular carcinomas.
出处
《中华肝脏病杂志》
CAS
CSCD
北大核心
2008年第12期905-908,共4页
Chinese Journal of Hepatology
关键词
磁共振成像
肝肿瘤
动态增强
Magnetic resonance imaging
Liver neoplasms
Dynamic contrast-enhanced
