摘要
测定并分析72例脑梗死及60例多梗死性痴呆（MID）患者、60例健康体检者（对照组）血清中抵抗素、神经元特异性烯醇化酶（NSE）浓度。结果示脑梗死急性期患者血清抵抗素、NSE浓度明显高于对照组（P〈0．01）；而恢复期患者血清抵抗素、NSE的浓度与对照组差异无统计学意义（P〉0．05）。MID患者抵抗素浓度与对照组及脑梗死恢复期之间差异无统计学意义（P〉0．05）；而NSE浓度低于对照组及脑梗死恢复期（P〈0．05）。提示检测血清抵抗素和NSE对MID患者病情及预后的判断有重要意义。
Serum concentrations of resistin and neuron-specific enolase （NSE） were determined in 72 patients with cerebral infarction （ CI ） , 60 patients with multi-infarct dementia （ MID ）, and 60 healthy controls by means of ELISA. Our data showed that serum resistin and NSE in the CI acute phase group were significantly higher than those in the normal control group （P 〈 0. 01 ）. No significant difference was found in serum resistin and NSE between the CI recovery phase group and normal controls group. Moreover, no significant difference was found in serum resistin between the MID group and CI recovery phase and normal control groups （ P 〉 0.05 ） ; but NSE was relatively lower （ P 〈 0. 05 ）. This study suggest that serum resistin and NSE might be of great significance to patient＇s condition and prognosis.
出处
《中华全科医师杂志》
2008年第12期849-850,共2页
Chinese Journal of General Practitioners
关键词
脑梗塞
痴呆
多发性梗塞症
Brain infarction
Dementia,multi-infarct
