摘要
目的探讨根除幽门螺杆菌(HP)与功能性消化不良(FD)患者消化不良症状的改善情况,分析功能性消化不良与幽门螺杆菌之间的关系。方法将幽门螺杆菌阳性的功能性消化不良患者100例随机分为治疗组和对照组各50例。治疗组予根除HP疗法:奥美拉唑+阿莫西林+甲硝唑三联疗法;对照组给予安慰剂(两组均据个体化原因都适当予胃动力药、质子泵抑制剂等)。停药后4周行14C-尿素呼气试验检测HP,对所有患者症状改善进行评分与治疗前和随访1年后再对比。结果治疗组50例HP根除者43例(86%)。治疗组HP根除者与HP未根除者治疗后1年,消化不良症状评估改善比较差异,有统计学意义(P<0.05)。两组治疗后1年,治疗组较对照组的症状改善更为明显。结论根除HP对改善FD症状是必要的。
Objective To discuss the situation on eradication of Hp and FD and analyze their relationship. Methods 100 cases of FD patient with Hp positive were divided into therapy group and control group. The therapy group was treated with omeprazole, amoxil and arilin. The control group was treated with placebo. The Hp was detected with 14C urea respiratory test. The symptoms before therapy and after therapy were assessed. Results There were 43 cases in therapy group eradicated of Hp. There was significant difference between two groups after one year follow - up with FD with significant difference. Conclusion The eradication of Hp might be important to improve FD.
出处
《黑龙江医学》
2008年第12期920-921,共2页
Heilongjiang Medical Journal
