摘要
目的:探讨MRI对鼻咽癌(NPC)侵犯范围及增强放疗靶区勾画的影响.方法:分析我院经病理证实的初诊NPC患者37例的影像学资料,治疗前短期内均行CT与MRI检查,对比其向周围结构侵犯和转移的异同;并采用随机化分组抽签法,抽取20名患者,在CT,MRI状态下分别勾画鼻咽原发肿瘤范围(GTVnx).结果:CT,MRI在咽后淋巴结转移、斜坡侵犯和椎前软组织受侵率方面,差异具有统计学意义(P<0.05);MRI确定的GTVnx较CT平均增加43.78%,差异具有统计学意义(P=0.000).结论:MRI对NPC的侵犯范围的界定及靶区勾画较CT有优势,联合应用更有价值.
AIM： To investigate the influence of MRI on the involved structure of nasopharynx and the grass tumor volume of nasopharynx （GTVnx） of the intensity modulated radiation therapy （IMRT） in nasopharyngeal carcinoma （ NPC ）. METHODS： Thirty-seven cases of NPC confirmed by pathology were reviewed. All cases undergone CT and MRI scanning in 1 week before treatment. The manifestations and patterns of MRI and CT were observed in NPC. Twenty patients were picked in this study for drawing GTVnx. GTVnx-based CT and MRI were evaluated in the target contour of IMRT in NPC. RESULTS： The involvement rates of the following structures which were shown on CT and MRI had obvious difference： retropharyngeal node, anterior border of foramen magnum and prevertebral muscle. Compared with CT, GTVnx confirmed by MRI was increased 43.78% , the difference being statistically significant （ P = 0. 000 ）. CONCLUSION ： MRI is superior to CT in diagnosis, staging and target contouring for NPC. Combined application of CT and MRI is better than the single.
出处
《第四军医大学学报》
北大核心
2008年第23期2167-2169,共3页
Journal of the Fourth Military Medical University
关键词
鼻咽肿瘤
MRI
CT
GTVnx
nasopharyngeal neoplasms
MRI
CT
grass targetvolume
