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细胞凋亡与动脉粥样硬化斑块稳定性关系的研究进展 被引量:3

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摘要 细胞凋亡,是指细胞在一定的生理或病理条件下,遵循自身程序自己结束其生命的程序性死亡。它是有一系列酶参与、由基因控制的一个主动的、高度有序的死亡过程,表现为细胞浆浓缩,染色质固缩,最后形成多个凋亡小体而被吞噬。对生物机体的正常发育及自身稳定具有极其重要的作用。细胞凋亡功能的失控、抑制或增加均会引起机体平衡失调,是多种疾病产生的重要原因之一。近年来发现细胞凋亡对不稳定的动脉粥样硬化斑块形成有一定作用,在预防和干预斑块进展方面有重要临床意义。
作者 何晓芬 张茁
出处 《中华老年心脑血管病杂志》 CAS 北大核心 2008年第12期955-956,共2页 Chinese Journal of Geriatric Heart,Brain and Vessel Diseases
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参考文献14

  • 1Virmani R, Burke AP, Farb A, et al. Pathology of the vulnerable plaque. J Am Coil Cardiol, 2006,47 : C13-C18.
  • 2Scarabelli TM, Knight R, Stephanou A, et al. Clinical implications of apoptosis in ischemic myocardium. Curr Probl Cardiol, 2006,31 : 181-264.
  • 3Chen J, Mehta JL, Haider N, et al. Role of caspases in ox-LDL-induced apoptotic cascade in human coronary artery endothelial cells. Circ Res,2004,94:370-376.
  • 4Lee HY,You HJ,Won JY,et al. Forkheed factor,Foxo3a,in duces apoptosis of endothelial cells through activation of ma trix metalloproteinases. Arterioscler Thromb Vasc Biol, 2008 28:302-308.
  • 5Banff C, Brioschi M, Wait R. Proteome of endothelial cell-derived procoagulant microparticles. Proteomics, 2005,17 : 4443- 4455.
  • 6Trostdorf F,Landgraf C,Kablau M,et al. Increased endothelial cell apoptosis in symptomatic high-grade carotid artery stenosis : preliminary data. Eur J Vasc Endovasc Surg, 2007,33 : 65-68.
  • 7Chen F, Eriksson P, Kimura T, et al. Apoptosis and angiogenesis are induced in the unstable coronary atherosclerotic plaque. Coron Artery Dis, 2005,16 : 191-197.
  • 8Trostdorf F, Buchkremer M, Harmjanz A, et al. Fibrous cap thickness and smooth muscle cell apoptosis in high-grade carotid artery stenosis. Eur J Vase Endovasc Surg, 2005,29:528-535.
  • 9Clarke M,Bennett M. The emerging role of vascular smooth muscle ceil apoptosis in atherosclerosis and plaque stability. Am J Nephrol, 2006,26 : 531-535.
  • 10Hartung D, Sarai M, Petrov A, et al. Resolution of apoptosis in atherosclerotic plaque by dietary modification and statin therapy. J Nuel Med,2005,46:2051-2056.

同被引文献36

  • 1裴志勇.不稳定性冠状动脉粥样硬化斑块的研究进展[J].临床内科杂志,2002,19(S1):5-7. 被引量:2
  • 2顾耘.软脉煎治疗颈动脉粥样硬化的临床研究[J].辽宁中医杂志,2004,31(8):634-636. 被引量:15
  • 3郭峰,朱炳阳,迟秀玲,黄红林.迷迭香酸抗过氧化氢诱导血管平滑肌细胞凋亡作用的研究[J].中国药理学通报,2007,23(3):365-370. 被引量:27
  • 4Lakatta EG,Levy D. Arterial and cardiac aging:major shareholders cardiovascular disease enterprises part I :aging arteries:a "set up" for vascular disease. Circulation, 2003, 107: 139 -146.
  • 5Najjar SS, ScuteriA, Lakatta EG. Arterial aging: is it an immutable cardiovascular risk factor? Hypertension, 2005,46: 454- 462.
  • 6Holaj R, Spacil J, Petrasek J, et al. Intima-media thickness of the common carotid artery is the significant predictor of angiographically proven coronary artey disease. Can J Cardiol, 2003,19:670-676.
  • 7Pezet M, Jacob MP, Escoubet B, et al. Elastin haploinsufficiency induces alternative aging processes in the aorta. Rejuvenation Res, 2008 : 11 : 970 112.
  • 8Fuster J J, Andres V. Telomere biology and cardiovascular disease. Circ Res, 2006,99 : 1167-1180.
  • 9Asai K,Kudej RK,Shen YT,et al. Peripheral vascular endothelial dysfunction and apoptosis in old monkeys. Arterioscler Thromb Vasc Biol,2000,20:1493- 1499.
  • 10Sanchez T, Skoura A, Wu MT, et al. Induction of vascular permeability by the sphingosine-l-phosphate receptor-2 (S1P2R) and its downstream effectors ROCK and PTEN. Arterioscler Thromb Vasc Biol,2007,27 : 1312-1318.

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