摘要
目的调查老年人轻度认知功能损害（MCI）的患病率，比较广义MCI和Petersen标准诊断遗忘型MCI（A—MCI）的异同。方法选择南京军区年龄≥70岁的离休老干部586例，进行认知功能调查，将符合广义MCI的104例患者分为MCI组，将非MCI患者482例分为正常组。采用广义MCI和A—MCI进行神经心理检查，对2种诊断标准MCI患病率比较。结果MCI组患者年龄较正常组高偏。与A—MCI 59例（10．07％）比较，广义MCI 104例（17．75％），患病率升高；广义MCI中主观记忆障碍77例（74％），较A—MCI 59例（100％）低。结论广义MCI较A—MCI诊断的患病率高，其包涵了更多类型的痴呆前期表现，有利于早期发现MCI及防治。
Objective To observe the prevalence of mild cognitive impairment（MCI） in an elderly cohort in comparison with the frequency of MCI by Petersen＇s diagnostic criteria. Methods 586 participants aged over 70 years underwent neuropsychological assessment. The prevalence of MCI was assessed using generalized diagnostic criteria and compared with the frequency of MCI diagnosed by Petersen＇s diagnostic criteria, Results MCI was present in 104 subjects（17.75%） who were older than normal subjects. In comparison with MCI diagnosed by Petersen＇ s criteria （10.07%）, the prevalence of MCI was higher, but the prevalence of subjective cognitive dysfunction（74%） was lower than that diagnosed by Petersen＇s criteria（100%）. Conclusions The prevalence of MCI diagnosed by generalized diagnostic criteria of MCI adopted in this investigation was higher than that according to Petersen＇s. The generalized diagnostic criteria include more types of high-risk subjects who will develope dementia later and this is beneficial to monitoring preclinical state of dementia.
出处
《中华老年心脑血管病杂志》
CAS
北大核心
2008年第12期920-923,共4页
Chinese Journal of Geriatric Heart,Brain and Vessel Diseases
基金
南京军区科技基金资助（07M077）
关键词
认知障碍
记忆障碍
痴呆
危险因素
诊断
cognition disorders
memory disorders
dementia
risk factors
diagnosis
