摘要
大鼠在某煤气厂轻、中、重不同空气污染现场自然吸入5天,检测其肺巨噬细胞(AM)数,AMFc受体以及肺有关淋巴结(LALN)和脾脏的抗体形成细胞数(PFC)。结果发现AM数和脾脏的PFC数在各个暴露现场无明显改变,AMFc受体数在重污染现场呈抑制,而LALN的PFC被激活。此外大鼠在中污染现场自然吸入5、14、30、60天,观察上述指标以及T淋巴细胞转化功能,结果发现除了AM数在各时期均未发生变化外,Fc受体数、脾和LALN的PFC数均在吸入早期被激活,后期被抑制,而脾和LALN的T淋巴细胞转化功能早期未发生明显变化,后期则被抑制。
This paper describes the change in immune function of rats exposed naturally to various levels of air pollution in a gas plant for different periods of time.Following field exposure for 5 days in light, medium and heavy air pollution areas, the Significant differences in the number of alvedlar macrophages(AM) and the plaque-forming cells ( PFC) in spleen were found. The number of AMFc receptors decreased and PFCs in lung-associated lymph nodes ( LALN ) increased in rats exposed in the heavy air pollution area After the rats were exposed in the medium pollution area for 5, 14, 30 and 60 days, the number of Fc receptors and PFCs in spleen and in LALN showed an increase initially then followed by a decrease The function of T-lymphocyte transformation had not changed in the early time of exposure but was inhibited cater.
出处
《环境与健康杂志》
CAS
CSSCI
CSCD
北大核心
1990年第1期4-7,共4页
Journal of Environment and Health
