摘要
目的研究情绪障碍对癌症患者内分泌以及免疫因子的影响。方法对48例初次接受放化疗的癌症患者进行HAMA、EPQ、HAMD、SSRS等量表测试,采用放射免疫测定法测定T3、T4、TSH、IL-2、TNF-a,用t检验、多元回归分析。结果抑郁组与无抑郁组比较T3、T4、TSH、IL-2、TNF-a之间无显著性差异(P>0.05);焦虑组与无焦虑组比较两组TNF-a有显著差异。结论抑郁情绪对癌症患者的T3、T4、TSH、IL-2、TNF-a无影响,癌症患者血液中TNF-a的浓度与性别、精神质个性、焦虑等多因素有关。
Objective To cancer patients. Methods study the effect of emotional disorder on endocrine secretion and immune factors of A total of 48 cancer patients were estimated by Hamilton Depression Scale （HAMD）, Eysenck Personality Questionnaire （EPQ）, Social Support Rating Scale（SSRS） ,and Hamihon Anxiety Scale （HAMA）. Radioimmunoassay was used to determine T3、T4、TSH、IL-2,TNF-α. T-check and multiple regression analysis were used to analyze the data. Results There were no significant differences in T3、T4、TSH、IL-2 and TNF-α between patients depression with and patients without depression. There had significant difference of TNF--a between patients with anxiety and patients without anxiety. Conclusion Depressive mood would not affect cancer patients＇ T3、T4、TSH、IL-2 and TNF-α .TNF-α of cancer patients is related with sex,psyche nature,anxiety and so on.
出处
《精神医学杂志》
2008年第6期429-431,共3页
Journal of Psychiatry
关键词
癌症
抑郁
焦虑
内分泌免疫因子
Cancer Depression Anxiety Endocrine immune factor
